0001193125-05-051266 Sample Contracts

CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION AMENDMENT NO. 1 TO SECOND AMENDED AND RESTATED...
And Supply Agreement • March 15th, 2005 • Nanogen Inc • Laboratory analytical instruments

This Amendment No. 1 to Second Amended and Restated Collaboration, License and Supply Agreement (the “Amendment”) is entered into this 26TH day of July, 2002.

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SECOND AMENDED AND RESTATED COLLABORATION, LICENSE AND SUPPLY AGREEMENT
License and Supply Agreement • March 15th, 2005 • Nanogen Inc • Laboratory analytical instruments • California

This Second Amended and Restated Collaboration, License and Supply Agreement (“Agreement”) dated as of August 17, 2000 (“Second Amendment Date”), amends and restates the License and Supply Agreement (the “Original Agreement”) dated as of January 11, 1999 (“Effective Date”) as amended June 30, 1999, and as amended by the Amended and Restated License and Supply Agreement dated as of November 1, 1999 (the “First Amended and Restated Agreement”) between EPOCH PHARMACEUTICALS, INC., (doing business as Epoch Biosciences, Inc.,) 12277 134th Court NE, Suite 100, Redmond, WA (“Epoch”) and PE CORPORATION (formerly known as THE PERKIN-ELMER CORPORATION) having its Applied Biosystems Group at 850 Lincoln Centre Drive, Foster City, CA 94404 (“ABG”).

EPOCH BIOSCIENCES, INC.
Nonqualified Stock Option Agreement • March 15th, 2005 • Nanogen Inc • Laboratory analytical instruments
CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION FIRST SIDE AGREEMENT
First Side Agreement • March 15th, 2005 • Nanogen Inc • Laboratory analytical instruments

This First Side Agreement (“First Side Agreement”), effective as of the 1st day of November, 2001 (“First Side Agreement Effective Date”), is by and between EPOCH BIOSCIENCES, INC., having a principal place of business at 21720 23rd Road SE, Bothell, Washington 98021 (“Epoch”), and PE CORPORATION (NY), through its Applied Biosystems Group, having a principal place of business at 850 Lincoln Centre Drive, Foster City, California 94404 (“ABG”).

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