Collaboration, License and Supply Agreement Sample Contracts

EXHIBIT 10.19 CONFIDENTIAL TREATMENT REQUESTED BY QLT INC. COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply Agreement • March 1st, 2007 • QLT Inc/Bc • Pharmaceutical preparations • New York
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THIRD AMENDMENT to the Collaboration, License and Supply Agreement, dated July 6, 2004 by and between Acusphere Inc. (“Acusphere”) and Nycomed Danmark ApS (“Nycomed”)
Collaboration, License and Supply Agreement • June 26th, 2008 • Acusphere Inc • Pharmaceutical preparations

This Third Amendment (the “Third Amendment”), effective as of June 4 2008, is entered into by and between Acusphere and Nycomed (the “Parties”).

Sample 1
FIRST AMENDMENT to the Collaboration, License and Supply Agreement, dated July 6, 2004 by and between Acusphere Inc. (“Acusphere”) and Nycomed Danmark ApS (“Nycomed”)
Collaboration, License and Supply Agreement • October 24th, 2005 • Acusphere Inc • Pharmaceutical preparations

This First Amendment (the “First Amendment”), effective as of October 19, 2005, is entered into by and between Acusphere and Nycomed (the “Parties”).

Sample 1
THIRD AMENDMENT TO THE COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply Agreement • March 13th, 2015 • Alexza Pharmaceuticals Inc. • Pharmaceutical preparations

This THIRD AMENDMENT TO THE COLLABORATION, LICENSE AND SUPPLY AGREEMENT (the “Third Amendment”) amends the Agreement (as defined below) and is effective as of October 24, 2014 (the “Third Amendment Effective Date”), by and between ALEXZA PHARMACEUTICALS, INC., a company organized under the laws of the State of Delaware, United States (“Alexza”), and having a principal place of business at 2091 Stierlin Court, Mountain View, CA 94043, United States, and GRUPO FERRER INTERNACIONAL, S.A., a company organized under the laws of Spain (“Ferrer”), having its registered office at Av. Diagonal 549, E-08029 Barcelona, Spain.

Sample 1
CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION AMENDMENT NO. 1 TO SECOND AMENDED AND RESTATED...
Collaboration, License and Supply Agreement • March 15th, 2005 • Nanogen Inc • Laboratory analytical instruments

This Amendment No. 1 to Second Amended and Restated Collaboration, License and Supply Agreement (the “Amendment”) is entered into this 26TH day of July, 2002.

Sample 1
EXHIBIT 10.21.1 CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24B-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION SECOND AMENDED AND RESTATED...
Collaboration, License and Supply Agreement • March 29th, 2002 • Epoch Biosciences Inc • In vitro & in vivo diagnostic substances • California
Sample 1
AMENDMENT TO COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply Agreement • March 12th, 2012 • Alexza Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This AMENDMENT TO THE COLLABORATION, LICENSE AND SUPPLY AGREEMENT (the “Amendment”) is effective as of March 5, 2012 (the “Amendment Effective Date”) by and between ALEXZA PHARMACEUTICALS, INC., a company organized under the laws of the State of Delaware, United States (“Alexza”). and having a principal place of business at 2091 Stierlin Court, Mountain View, CA 94043, United States, and GRUPO FERRER INTERNACIONAL, S.A., a company organized under the laws of Spain (“Ferrer”), having its registered office at Av. Diagonal 549, E-08029 Barcelona, Spain.

Sample 1
AMENDMENT NO. 2 TO SECOND AMENDED AND RESTATED COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply Agreement • March 16th, 2006 • Nanogen Inc • Laboratory analytical instruments • California

THIS AMENDMENT NO. 2 TO SECOND AMENDED AND RESTATED COLLABORATION, LICENSE AND SUPPLY AGREEMENT (the “2nd Amendment”), is entered into as of December 31, 2005 (the “2nd Amendment Date”) by and between EPOCH BIOSCIENCES, INC., with offices at 21720 23rd Drive S.E., Suite 150, Bothell, WA ( “Epoch”), a wholly owned subsidiary of Nanogen, Inc., with offices at 10398 Pacific Center Ct., San Diego, CA 92121 (“Nanogen”); and APPLERA CORPORATION, through its Applied Biosystems group, with offices at 850 Lincoln Centre Drive, Foster City, CA 94404 (“ABG”). Each of Epoch and ABG is individually referred to as a “Party” and, collectively, as “Parties”.

Sample 1
SECOND AMENDMENT TO COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply Agreement • March 13th, 2015 • Alexza Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This SECOND AMENDMENT TO THE COLLABORATION, LICENSE AND SUPPLY AGREEMENT (the “Second Amendment”) is effective as of 6th November, 2013 (the “Second Amendment Effective Date”) by and between ALEXZA PHARMACEUTICALS, INC., a company organized under the laws of the State of Delaware, United States (“Alexza”), and having a principal place of business at 2091 Stierlin Court, Mountain View, CA 94043, United States, and GRUPO FERRER INTERNACIONAL, S.A., a company organized under the laws of Spain (“Ferrer”), having its registered office at Av. Diagonal 549, E-08029 Barcelona, Spain.

Sample 1
SECOND AMENDED AND RESTATED COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply Agreement • March 15th, 2005 • Nanogen Inc • Laboratory analytical instruments • California

This Second Amended and Restated Collaboration, License and Supply Agreement (“Agreement”) dated as of August 17, 2000 (“Second Amendment Date”), amends and restates the License and Supply Agreement (the “Original Agreement”) dated as of January 11, 1999 (“Effective Date”) as amended June 30, 1999, and as amended by the Amended and Restated License and Supply Agreement dated as of November 1, 1999 (the “First Amended and Restated Agreement”) between EPOCH PHARMACEUTICALS, INC., (doing business as Epoch Biosciences, Inc.,) 12277 134th Court NE, Suite 100, Redmond, WA (“Epoch”) and PE CORPORATION (formerly known as THE PERKIN-ELMER CORPORATION) having its Applied Biosystems Group at 850 Lincoln Centre Drive, Foster City, CA 94404 (“ABG”).

Sample 1
COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply Agreement • March 12th, 2012 • Alexza Pharmaceuticals Inc. • Pharmaceutical preparations

This COLLABORATION, LICENSE AND SUPPLY AGREEMENT (“Agreement”) is entered into as of October 5th, 2011 (the “Effective Date”) between ALEXZA PHARMACEUTICALS, INC., a company organized under the laws of the State of Delaware, United States (“Alexza”), and having a principal place of business at 2091 Stierlin Court, Mountain View, CA 94043, United States, and GRUPO FERRER INTERNACIONAL, S.A., a company organized under the laws of Spain (“Ferrer”), having its registered office at Av. Diagonal 549, E-08029 Barcelona, Spain.

Sample 1
SECOND AMENDMENT to the Collaboration, License and Supply Agreement, dated July 6, 2004 by and between Acusphere Inc. (“Acusphere”) and Nycomed Danmark ApS (“Nycomed”)
Collaboration, License and Supply Agreement • February 14th, 2006 • Acusphere Inc • Pharmaceutical preparations

This Second Amendment (the “Second Amendment”), effective as of 9th February, 2006, is entered into by and between Acusphere and Nycomed (the “Parties”).

Sample 1
FOURTH AMENDMENT to the Collaboration, License and Supply Agreement, dated July 6, 2004 by and between Acusphere Inc. (“Acusphere”) and Nycomed Danmark ApS (“Nycomed”)
Collaboration, License and Supply Agreement • September 8th, 2008 • Acusphere Inc • Pharmaceutical preparations

This Fourth Amendment (the “Fourth Amendment”), effective as of September 3, 2008, is entered into by and between Acusphere and Nycomed (the “Parties”).

Sample 1
FOURTH AMENDMENT TO COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply Agreement • August 6th, 2015 • Alexza Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This FOURTH AMENDMENT TO THE COLLABORATION, LICENSE AND SUPPLY AGREEMENT (the “Fourth Amendment”) is effective as of June 16, 2015 (the “Fourth Amendment Effective Date”) by and between ALEXZA PHARMACEUTICALS, INC., a company organized under the laws of the State of Delaware, United States (“Alexza”), and having a principal place of business at 2091 Stierlin Court, Mountain View, CA 94043, United States, and GRUPO FERRER INTERNACIONAL, S.A., a company organized under the laws of Spain (“Ferrer”), having its registered office at Av. Diagonal 549, E-08029 Barcelona, Spain.

Sample 1
COLLABORATION, LICENSE AND SUPPLY AGREEMENT dated as of February 2, 2012 between Becton, Dickinson and Company, through its BD Diagnostics – Diagnostic Systems business unit and Strategic Diagnostics Inc., d/b/a SDIX
Collaboration, License and Supply Agreement • February 8th, 2012 • Strategic Diagnostics Inc/De/ • Miscellaneous chemical products • New York
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