0001193125-08-038683 Sample Contracts

FOURTH LEASE AMENDMENT TO LEASE AGREEMENT
Lease Agreement • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research • North Carolina

THIS FOURTH AMENDMENT TO LEASE AGREEMENT (hereinafter referred to as the “Amendment”) is made as of the day of 2005, by and between DUKE REALTY LIMITED PARTNERSHIP, an Indiana limited partnership doing business in North Carolina as Duke Realty of Indiana Limited Partnership, successor by merger to Weeks Realty, L.P. (hereinafter referred to as “Landlord”) and PPD DEVELOPMENT LP, a Texas limited partnership and successor in interest to PPD Development, Inc. (hereinafter referred to as “Tenant”).

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SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT
Lease Agreement • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research • North Carolina

THIS SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT (hereinafter referred to as the “Seventh Amendment”) is made as of the 6th day of February 2006, by and between DUKE REALTY LIMITED PARTNERSHIP, an Indiana limited partnership doing business in North Carolina as Duke Realty of Indiana Limited Partnership, successor by merger to Weeks Realty, L.P. (hereinafter referred to as “Landlord”) and PPD DEVELOPMENT LP, a Texas limited partnership and successor in interest to PPD Development, Inc. (hereinafter referred to as “Tenant”).

EIGHTH LEASE AMENDMENT TO LEASE AGREEMENT
Eighth Lease • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research • North Carolina

THIS EIGHTH LEASE AMENDMENT TO LEASE AGREEMENT (hereinafter referred to as the “Amendment”) is made as of the 24th day of September 2007, by and between DUKE REALTY LIMITED PARTNERSHIP, an Indiana limited partnership doing business in North Carolina as Duke Realty of Indiana Limited Partnership, successor by merger to Weeks Realty, L.P. (hereinafter referred to as “Landlord”) and PPD DEVELOPMENT LP, a Texas limited partnership and successor in interest to PPD Development, Inc. (hereinafter referred to as “Tenant”).

SIXTH LEASE AMENDMENT TO LEASE AGREEMENT
Lease Agreement • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research • North Carolina

THIS SIXTH LEASE AMENDMENT TO LEASE AGREEMENT (hereinafter referred to as the 30th day of December 2005, by and between DUKE REALTY LIMITED PARTNERSHIP, an Indiana limited partnership doing business in North Carolina as Duke Realty of Indiana Limited Partnership, successor by merger to Weeks Realty, L.P. (hereinafter referred to as “Landlord”) and PPD DEVELOPMENT LP, a Texas limited partnership and successor in interest to PPD Development, Inc. (hereinafter referred to as “Tenant”).

TENTH AMENDMENT TO LEASE AMENDMENT
Lease Amendment • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research

THIS TENTH AMENDMENT TO LEASE AGREEMENT (this “Amendment”) is made and entered into this day of September, 2007, by and between Greenway Office Center L.L.C. (the “Landlord”) and PPD Developments, LLP (the “Tenant”).

FIRST AMENDMENT TO LEASE
Pharmaceutical Product Development Inc • February 26th, 2008 • Services-commercial physical & biological research

Fixed Rent for Suite L is set forth below, payable in the monthly installments as set forth below and otherwise in accordance with the terms of the Lease, as amended hereby:

NINTH LEASE AMENDMENT- PPD Development, LLC
Pharmaceutical Product Development Inc • February 26th, 2008 • Services-commercial physical & biological research

THIS NINTH AMENDMENT of Lease (this “Amendment”) is made and entered into this 31st day of August, 2007, by and between Greenway Office Center L.L.C. (the “Landlord”) and PPD Developments, LLC. (the “Tenant” ).

SEVERANCE AGREEMENT
Severance Agreement • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research • North Carolina

THIS AGREEMENT, effective the 1st day of January, 2001, by and between Pharmaceutical Product Development, Inc. and its subsidiaries and affiliates (collectively, “PPD”) and (“Employee”).

FIFTH LEASE AMENDMENT TO LEASE AGREEMENT
Lease Agreement • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research • North Carolina

THIS FIFTH LEASE AMENDMENT TO LEASE AGREEMENT (hereinafter referred to as the “Amendment”) is made as of the 7 day of July 2005, by and between DUKE REALTY LIMITED PARTNERSHIP, an Indiana limited partnership doing business in North Carolina as Duke Realty of Indiana Limited Partnership, successor by merger to Weeks Realty, L.P. (hereinafter referred to as “Landlord”) and PPD DEVELOPMENT LP, a Texas limited partnership and successor in interest to PPD Development, Inc. (hereinafter referred to as “Tenant”).

EIGHTH AMENDMENT TO LEASE AGREEMENT
Lease Agreement • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research

THIS EIGHTH AMENDMENT TO LEASE AGREEMENT (this “Amendment”) is made and entered into this 1st day of March, 2006, by and between GREENWAY PROPERTIES, INC. (f.k.a. Western Center Properties, Inc.) (“Landlord”) and PPD DEVELOPMENT, LP (“Tenant”).

THIRD LEASE AMENDMENT TO LEASE AGREEMENT
Lease Agreement • February 26th, 2008 • Pharmaceutical Product Development Inc • Services-commercial physical & biological research • North Carolina

THIS THIRD AMENDMENT TO LEASE AGREEMENT (hereinafter referred to as the “Amendment”) is made as of the 22 day of September 2003, by and between DUKE REALTY LIMITED PARTNERSHIP, an Indiana limited partnership doing business in North Carolina as Duke Realty of Indiana Limited Partnership, successor by merger to Weeks Realty, L.P. (hereinafter referred to as “Landlord”) and PPD Development, LP, a Texas limited partnership and successor in interest to PPD Development, Inc. (hereinafter referred to as “Tenant”).

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