0001193125-08-182844 Sample Contracts

SALIX PHARMACEUTICALS, LTD. as Issuer AND U.S. BANK NATIONAL ASSOCIATION as Trustee INDENTURE Dated as of August 22, 2008 5.5% Convertible Senior Notes due 2028
Indenture • August 22nd, 2008 • Salix Pharmaceuticals LTD • Pharmaceutical preparations • New York

INDENTURE dated as of August 22, 2008 between Salix Pharmaceuticals, Ltd., a Delaware corporation, as issuer (the “Company”) and U.S. Bank National Association, as trustee (the “Trustee”).

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55,000,000 AGGREGATE PRINCIPAL AMOUNT Salix Pharmaceuticals, Ltd. 5.5% CONVERTIBLE SENIOR NOTES DUE 2028 Purchase Agreement dated August 18, 2008
Purchase Agreement • August 22nd, 2008 • Salix Pharmaceuticals LTD • Pharmaceutical preparations • New York
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