0001193125-09-001870 Sample Contracts

AMENDMENT CONSENT
Bema License Agreement • January 6th, 2009 • Biodelivery Sciences International Inc • Pharmaceutical preparations • North Carolina

This AMENDMENT CONSENT (the “Consent”) is entered this January 2, 2009 (the “Consent Date”) by Arius Pharmaceuticals, Inc. (“Arius”) and Arius Two, Inc. (“Arius Two”).

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AMENDMENT TO LICENSE AND DEVELOPMENT AGREEMENT
License and Development Agreement • January 6th, 2009 • Biodelivery Sciences International Inc • Pharmaceutical preparations • New York

This AMENDMENT TO LICENSE AND DEVELOPMENT AGREEMENT (the “Amendment”) is entered this January 2, 2008 (the “Amendment Date”), by BioDelivery Sciences International, Inc., a Delaware corporation with offices at 801 Corporate Center Drive, Suite 210, Raleigh, North Carolina 27607 (“Parent”), its wholly-owned subsidiary Arius Pharmaceuticals, Inc., a Delaware corporation with offices at the same address (“Arius”, and together with Parent, “BDSI”) and Meda AB, a Swedish corporation located at Pipers väg 2 A, SE-170 09, Solna, Sweden (“Meda”),

CONSENT AGREEMENT
Consent Agreement • January 6th, 2009 • Biodelivery Sciences International Inc • Pharmaceutical preparations • New York

This CONSENT AGREEMENT (the “Consent”) is entered this January 2, 2009, by BioDelivery Sciences International, Inc., with offices at 801 Corporate Center Drive, Suite 210, Raleigh, North Carolina 27607, its wholly-owned subsidiary Arius Pharmaceuticals, Inc., with offices at the same address (“Arius”; with Parent, “BDSI”), and CDC IV, LLC, with offices at 47 Hulfish Street, Suite 310, Princeton, New Jersey 08542 (“CDC”).

AMENDMENT CONSENT
Bema License Agreement • January 6th, 2009 • Biodelivery Sciences International Inc • Pharmaceutical preparations • North Carolina

This AMENDMENT CONSENT (the “Consent”) is entered this January 2, 2009 (the “Consent Date”) by Arius Pharmaceuticals, Inc. (“Arius”) and Arius Two, Inc. (“Arius Two”).

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