Bema License Agreement Sample Contracts

SECOND AMENDMENT AGREEMENT
Bema License Agreement • September 10th, 2007 • Biodelivery Sciences International Inc • Pharmaceutical preparations • North Carolina

This SECOND AMENDMENT AGREEMENT (the “Amendment”) is entered this September 5, 2007 (the “Second Amendment Date”) by Arius Two, Inc. (“Arius Two”) and Arius Pharmaceuticals, Inc. (“Arius”).

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BEMA LICENSE AGREEMENT
Bema License Agreement • August 9th, 2006 • Biodelivery Sciences International Inc • Pharmaceutical preparations • North Carolina

This BEMA License Agreement (the “Agreement”) is made as of August 2, 2006 (the “Effective Date”) by and between Arius Two, Inc., a Delaware corporation with its principal office at 2501 Aerial Center Parkway, Suite 205, Morrisville, North Carolina 27560 USA (“Arius Two”), and Arius Pharmaceuticals, Inc., a Delaware corporation with a mailing address at 2501 Aerial Center Parkway, Suite 205, Morrisville, North Carolina 27560 USA (“Arius”). Arius Two and Arius are sometimes referred to collectively herein as the “Parties” or singly as a “Party.”

AMENDMENT CONSENT
Bema License Agreement • January 6th, 2009 • Biodelivery Sciences International Inc • Pharmaceutical preparations • North Carolina

This AMENDMENT CONSENT (the “Consent”) is entered this January 2, 2009 (the “Consent Date”) by Arius Pharmaceuticals, Inc. (“Arius”) and Arius Two, Inc. (“Arius Two”).

AMENDMENT CONSENT
Bema License Agreement • January 6th, 2009 • Biodelivery Sciences International Inc • Pharmaceutical preparations • North Carolina

This AMENDMENT CONSENT (the “Consent”) is entered this January 2, 2009 (the “Consent Date”) by Arius Pharmaceuticals, Inc. (“Arius”) and Arius Two, Inc. (“Arius Two”).

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