0001193125-09-258134 Sample Contracts

SECOND AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • December 22nd, 2009 • Arrowhead Research Corp • Services-commercial physical & biological research • Delaware

This Second Amended and Restated Investors’ Rights Agreement (the “Agreement”) is made as of the September 30, 2009, by and between Unidym, Inc., a Delaware corporation (the “Company”), each of the investors listed on Schedule A hereto (each of which is referred to in this Agreement as an “Investor”) and each of the stockholders listed on Schedule B hereto (each of which is referred to in this Agreement as a “Stockholder”).

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ARROWHEAD RESEARCH CORPORATION SUBSCRIPTION AGREEMENT
Subscription Agreement • December 22nd, 2009 • Arrowhead Research Corp • Services-commercial physical & biological research • Delaware
REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • December 22nd, 2009 • Arrowhead Research Corp • Services-commercial physical & biological research • Delaware

THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”) is made and entered into as of this 11th day of December, 2009 by and among Arrowhead Research Corporation, a Delaware corporation (the “Company”) and the purchasers of the Company’s Units (as defined below) listed on Exhibit A hereto, as may be amended from time to time (the “Investors”).

SUBSCRIPTION AGREEMENT
Subscription Agreement • December 22nd, 2009 • Arrowhead Research Corp • Services-commercial physical & biological research • California

THIS SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of the last date indicated on the signature pages hereto between Unidym, Inc., a Delaware corporation (the “Company”), and the undersigned investors parties hereto (each an “Investor” and collectively, the “Investors”).

AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • December 22nd, 2009 • Arrowhead Research Corp • Services-commercial physical & biological research

This Amendment (“Amendment”) to the Employment Agreement dated June 11, 2008 (“Agreement”) between Dr. Christopher Anzalone (“Executive”) and Arrowhead Research Corporation (“Company”), a Delaware corporation located at 201 S. Lake Avenue, Suite 703, Pasadena, CA 91101, is made and entered into as May 12, 2009 (“Effective Date”).

AMENDMENT TO SEVERANCE AGREEMENT
Severance Agreement • December 22nd, 2009 • Arrowhead Research Corp • Services-commercial physical & biological research

This Amendment (“Amendment”) to the Severance Agreement dated May 24, 2007 (“Agreement”) between R. Bruce Stewart (“Executive”) and Arrowhead Research Corporation (“Company”), a Delaware corporation located at 201 S. Lake Avenue, Suite 703, Pasadena, CA 91101, is made and entered into as May 12, 2009 (“Effective Date”).

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