0001193125-10-154113 Sample Contracts

NUVEEN MUNICIPAL HIGH INCOME OPPORTUNITY FUND 2 Common Stock ($0.01 par value) EQUITY DISTRIBUTION AGREEMENT
Equity Distribution Agreement • July 6th, 2010 • Nuveen Municipal High Income Opportunity Fund 2 • New York

Nuveen Investments, LLC, a Delaware limited liability company (the “Manager”), confirms its agreement, subject to the terms and conditions stated herein, to retain Stifel, Nicolaus & Company, Incorporated (the “Agent”) as the Manager’s exclusive sub-placement agent with respect to registered at-the-market offerings of 1,600,000 shares (the “Shares”) of the common stock, $0.01 par value per share (the “Common Stock”), of Nuveen Municipal High Income Opportunity Fund 2, a Massachusetts business trust (the “Fund”), on the terms set forth in Section 2 of this Equity Distribution Agreement (the “Agreement”). The Fund’s investment adviser is Nuveen Asset Management, a Delaware corporation (the “Adviser”). This Agreement constitutes a novation of, and supersedes, that certain Equity Distribution Agreement, dated November 23, 2009, among the Agent, the Fund, the Adviser and the Manager.

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