0001193125-10-180853 Sample Contracts

July 25, 2010
Placement Agent Agreement • August 6th, 2010 • Cell Therapeutics Inc • Pharmaceutical preparations • New York
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SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • August 6th, 2010 • Cell Therapeutics Inc • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of July 25, 2010, among Cell Therapeutics, Inc., a Washington corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

COMMON STOCK PURCHASE WARRANT To Purchase [—] Shares of Common Stock of CELL THERAPEUTICS, INC.
Common Stock Purchase Warrant • August 6th, 2010 • Cell Therapeutics Inc • Pharmaceutical preparations

THIS COMMON STOCK PURCHASE WARRANT (this “Warrant”) certifies that, for value received, [—] (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the six (6) month and one (1) day anniversary of the Initial Issuance Date (the “Initial Exercise Date”) and on or before the close of business on the four (4) year, six (6) month, and one (1) day anniversary of the Initial Issuance Date (the “Termination Date”) but not thereafter, to subscribe for and purchase from Cell Therapeutics, Inc., a Washington corporation (the “Company”), up to [—] shares (the “Warrant Shares”) of common stock, no par value per share (the “Common Stock”) of the Company; provided, however, that in no event shall Holder be entitled to subscribe for and purchase from the Company the Warrant Shares (or any portion thereof) unless and until (i) the shareholders of the Company approve, after the Initial Issuance Date, an amen

DRUG PRODUCT MANUFACTURING SUPPLY AGREEMENT
Drug Product Manufacturing Supply Agreement • August 6th, 2010 • Cell Therapeutics Inc • Pharmaceutical preparations • London

THIS DRUG PRODUCT MANUFACTURING SUPPLY AGREEMENT (“Agreement”) is made effective as of July 9, 2010 (the “Effective Date”) by and between NerPharMa, S.r.l. (“NPM”) Viale Pasteur, 10-20014 Nerviano (MI), Italy, and Cell Therapeutics, Inc. (“CTI”), having an office at 501 Elliott Avenue West, Suite 400, Seattle, WA 98119.

EXCHANGE AGREEMENT
Exchange Agreement • August 6th, 2010 • Cell Therapeutics Inc • Pharmaceutical preparations • New York

This EXCHANGE AGREEMENT (this “Agreement”) is made and entered into as of this 25th day of July, 2010, by and among Cell Therapeutics, Inc., a Washington corporation (the “Company”), and the parties listed on the signature pages hereto (each, a “Holder” and collectively, the “Holders”).

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