0001193125-11-324495 Sample Contracts

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. RESEARCH AND LICENSE AGREEMENT BY AND BETWEEN AVEO PHARMACEUTICALS, INC. AND CENTOCOR ORTHO BIOTECH INC.
Research and License Agreement • November 29th, 2011 • Aveo Pharmaceuticals Inc • Pharmaceutical preparations • New York

This Research and License Agreement, made this 31st day of May, 2011 (the “Effective Date”), is by and between AVEO Pharmaceuticals, Inc., a Delaware company, with principal offices located at 75 Sidney Street, Cambridge, MA 02139 (“AVEO”) and Centocor Ortho Biotech Inc., a Pennsylvania company, with principal offices located at 800/850 Ridgeview Road, Horsham, PA 19044 (“COBI”). Each of COBI and AVEO may be referred to, individually, as a “Party”, and, collectively, as the “Parties”.

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