0001193125-16-421460 Sample Contracts

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. MASSACHUSETTS INSTITUTE OF TECHNOLOGY AND VISTERRA INC. EXCLUSIVE PATENT LICENSE AGREEMENT
Exclusive Patent License Agreement • January 5th, 2016 • Visterra, Inc. • Pharmaceutical preparations • Massachusetts

This Agreement, effective as of the date set forth above the signatures of the parties below (the “EFFECTIVE DATE”), is between the Massachusetts Institute of Technology (“M.I.T.”), a Massachusetts corporation, with a principal office at 77 Massachusetts Avenue, Cambridge, MA 02139-4307 and Visterra, Inc. (“COMPANY”), a Delaware corporate, with a principal place of business at One Kendall Square, Suite B3301, Cambridge, MA 02139.

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AWARD/CONTRACT 1. THIS CONTRACT IS A RATED ORDER UNDER DPAS (15 CFR 700) u RATING PAGE OF PAGES 1 70 ASPR-BARDA 200 Independence Ave., S.W. Room. 640-G Washington DC 20201 ASPR-BARDA 330 Independence Ave., SW, Room. G644 Washington DC 20201 VISTERRA,...
Contract • January 5th, 2016 • Visterra, Inc. • Pharmaceutical preparations

This contract is for the advanced development of VIS410. Visterra, Inc. will develop a robust data package to support a BLA for the licensure of VIS410 as a treatment for severe/hospitalized influenza and patients at high risk of complications due to influenza infection. Options are also included for the treatment of pediatrics.

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. License and Collaboration Agreement Between Visterra, Inc. and Serum Institute of India Ltd. August 7, 2015
License and Collaboration Agreement • January 5th, 2016 • Visterra, Inc. • Pharmaceutical preparations • New York

This LICENSE AND COLLABORATION AGREEMENT (the “Agreement”) is entered into on August 7, 2015 (the “Effective Date”) between VISTERRA, INC., a Delaware corporation with its principal place of business at One Kendall Square, Suite B3301, Cambridge, MA 02139 (“Visterra”), and SERUM INSTITUTE OF INDIA LTD., a company incorporated under the Companies Act, 1956, and having its Registered Office at 212/2, Off Soli Poonawalla Road, Hadaspar, Pune 411028, India (“SIIL”). Visterra and SIIL are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. MASSACHUSETTS INSTITUTE OF TECHNOLOGY PARASOL THERAPEUTICS, INC. EXCLUSIVE PATENT LICENSE AGREEMENT
Exclusive Patent License Agreement • January 5th, 2016 • Visterra, Inc. • Pharmaceutical preparations • Massachusetts

This Agreement, effective as of the date set forth above the signatures of the parties below (the “EFFECTIVE DATE”), is between the Massachusetts Institute of Technology (“M.I.T.”), a Massachusetts corporation, with a principal office at 77 Massachusetts Avenue, Cambridge, MA 02139-4307 and Parasol Therapeutics, Inc. (“COMPANY”), a Delaware corporation, with a principal place of business at c/o Polaris Ventures, 1000 Winter Street, Waltham, Massachusetts 02451-1436.

CONSULTING AGREEMENT
Consulting Agreement • January 5th, 2016 • Visterra, Inc. • Pharmaceutical preparations • Massachusetts

THIS CONSULTING AGREEMENT (together with Exhibit A hereto, the “Agreement”) made as of February 17, 2013 (the “Effective Date”) is between Visterra, Inc., a Delaware corporation having an address at One Kendall Square, Suite B3301, Cambridge, MA 02142 (“Visterra”) and Ram Sasisekharan, Ph.D (“Consultant”), with an address at 77 Massachusetts Ave., Cambridge, MA. Visterra desires to have the benefit of Consultant’s knowledge and experience in the form of Consulting Services (defined below), and Consultant desires to provide Consulting Services to Visterra, all as provided in this Agreement.

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions.
Letter Agreement • January 5th, 2016 • Visterra, Inc. • Pharmaceutical preparations • Delaware

This amended and restated letter agreement (including all appendices and attachments hereto, the “Letter Agreement”) is entered into on November 7, 2013 and effective as of September 12, 2012, in connection with the investment by the Bill & Melinda Gates Foundation (the “Foundation”), a Washington charitable trust that is a tax-exempt private foundation, of a total of six million and eight hundred thousand dollars ($6,800,000) for Series A Preferred Stock of Visterra, Inc. (the “Company”) at the per share price of $1.00 (the “Foundation Investment”). This Letter Agreement replaces the letter agreement, dated September 12, 2012, between the Company and the Foundation in its entirety. The Foundation is making the Foundation Investment in accordance with the provisions of the investment documents executed in connection with the closing of the supplemental Series A Preferred Stock offering (“Supplemental Closing”), including, without limitation, the Amended and Restated Series A Convertibl

INDEMNIFICATION AGREEMENT
Indemnification Agreement • January 5th, 2016 • Visterra, Inc. • Pharmaceutical preparations • Delaware

THIS INDEMNIFICATION AGREEMENT (“Agreement”) is made as of [ ], by and between VISTERRA, INC., a Delaware corporation (the “Company”), and [ ] (the “Indemnitee”).

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