0001193125-17-365072 Sample Contracts

EIGER BIOPHARMACEUTICALS, INC., Issuer AND [TRUSTEE], Trustee FORM OF INDENTURE Dated as of [•], 20__ Debt Securities
Indenture • December 8th, 2017 • Eiger BioPharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

INDENTURE, dated as of [•], 20 , among EIGER BIOPHARMACEUTICALS, INC., a Delaware corporation (the “Company”), and [TRUSTEE], as trustee (the “Trustee”):

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EIGER BIOPHARMACEUTICALS, INC. AND , AS WARRANT AGENT FORM OF PREFERRED STOCK WARRANT AGREEMENT DATED AS OF [ ], 20
Preferred Stock Warrant Agreement • December 8th, 2017 • Eiger BioPharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

PREFERRED STOCK WARRANT AGREEMENT (this “Agreement”), dated as of between EIGER BIOPHARMACEUTICALS, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

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EIGER BIOPHARMACEUTICALS, INC. AND , AS WARRANT AGENT FORM OF COMMON STOCK WARRANT AGREEMENT DATED AS OF [ ], 20
Common Stock Warrant Agreement • December 8th, 2017 • Eiger BioPharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

COMMON STOCK WARRANT AGREEMENT (this “Agreement”), dated as of between EIGER BIOPHARMACEUTICALS, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

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EIGER BIOPHARMACEUTICALS, INC. AND , AS WARRANT AGENT FORM OF DEBT SECURITIES WARRANT AGREEMENT DATED AS OF [ ], 20
Warrant Agreement • December 8th, 2017 • Eiger BioPharmaceuticals, Inc. • Biological products, (no disgnostic substances) • New York

DEBT SECURITIES WARRANT AGREEMENT (this “Agreement”), dated as of between EIGER BIOPHARMACEUTICALS, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

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