0001193125-20-044722 Sample Contracts

Chiasma, Inc. Building C East Needham, MA 02494
Executive Employment Letter • February 21st, 2020 • Chiasma, Inc • Pharmaceutical preparations

This Amendment (the “Amendment”) to the Amended and Restated Executive Employment Letter dated February 23, 2018 (the “Agreement”) confirms the amended terms and conditions of your employment with Chiasma, Inc. (the “Company”) effective February 14, 2020. Except as expressly amended herein, the Agreement remains in full effect. Your Non-Competition, Non-Solicitation, Confidentiality and Assignment Agreement with the Company dated May 8, 2015 is unaltered and unamended by this Amendment and remains in full effect.

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Chiasma, Inc. Building C East Needham, MA 02494
Executive Employment Letter • February 21st, 2020 • Chiasma, Inc • Pharmaceutical preparations

This Amendment (the “Amendment”) to the Executive Employment Letter dated May 31, 2019 (the “Agreement”) confirms the amended terms and conditions of your employment with Chiasma, Inc. (the “Company”) effective February 14, 2020. Except as expressly amended herein, the Agreement remains in full effect. Your Employee Confidentiality, Assignment and Noncompetition Agreement with the Company dated May 31, 2019 is unaltered and unamended by this Amendment and remains in full effect.

Chiasma, Inc. Building C East Needham, MA 02494
Executive Employment Letter • February 21st, 2020 • Chiasma, Inc • Pharmaceutical preparations

This Amendment (the “Amendment”) to the Amended and Restated Executive Employment Letter dated May 31, 2019 (the “Agreement”) confirms the amended terms and conditions of your employment with Chiasma, Inc. (the “Company”) effective February 14, 2020. Except as expressly amended herein, the Agreement remains in full effect. Your Non-Competition, Non-Solicitation, Confidentiality and Assignment Agreement with the Company dated May 8, 2015 is unaltered and unamended by this Amendment and remains in full effect.

Chiasma, Inc. Building C East Needham, MA 02494
Executive Employment Letter • February 21st, 2020 • Chiasma, Inc • Pharmaceutical preparations

This Amendment (the “Amendment”) to the Amended and Restated Executive Employment Letter dated February 23, 2018 (the “Agreement”) confirms the amended terms and conditions of your employment with Chiasma, Inc. (the “Company”) effective February 14, 2020. Except as expressly amended herein, the Agreement remains in full effect. Your Non-Competition, Non-Solicitation, Confidentiality and Assignment Agreement with the Company dated September 23, 2015 is unaltered and unamended by this Amendment and remains in full effect.

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