0001193125-20-267263 Sample Contracts

OPTHEA LIMITED AND THE BANK OF NEW YORK MELLON As Depositary AND OWNERS AND HOLDERS OF AMERICAN DEPOSITARY SHARES Amended and Restated Deposit Agreement

Deposit Agreement • October 9th, 2020 • Opthea LTD • Biological products, (no disgnostic substances) • New York

• Contract Type
  Deposit Agreement
• Filed
  October 9th, 2020
• Company
  Opthea LTD
• Industry
  Biological products, (no disgnostic substances)
• Jurisdiction
  New York

Commercial License Agreement

Commercial License Agreement • October 9th, 2020 • Opthea LTD • Biological products, (no disgnostic substances)

• Contract Type
  Commercial License Agreement
• Filed
  October 9th, 2020
• Company
  Opthea LTD
• Industry
  Biological products, (no disgnostic substances)

OPTHEA LIMITED [●] American Depositary Shares Representing [●] Ordinary Shares (no par value) Underwriting Agreement

Underwriting Agreement • October 9th, 2020 • Opthea LTD • Biological products, (no disgnostic substances) • New York

• Contract Type
  Underwriting Agreement
• Filed
  October 9th, 2020
• Company
  Opthea LTD
• Industry
  Biological products, (no disgnostic substances)
• Jurisdiction
  New York

Date] [Director Name] Private and confidential Dear , Non-Executive Director Agreement

Non-Executive Director Agreement • October 9th, 2020 • Opthea LTD • Biological products, (no disgnostic substances)

• Contract Type
  Non-Executive Director Agreement
• Filed
  October 9th, 2020
• Company
  Opthea LTD
• Industry
  Biological products, (no disgnostic substances)

We are pleased to confirm your appointment to the board as a non-executive director of Opthea Limited (ACN 006 340 567) (Company), as well as, to the extent requested by the Company, its subsidiaries from time to time (Subsidiaries) (together, the Group).