0001193125-21-291044 Sample Contracts

METACRINE, INC. Shares of Common Stock ($0.0001 par value per share) SALES AGREEMENT

Sales Agreement • October 4th, 2021 • Metacrine, Inc. • Pharmaceutical preparations • New York

• Contract Type
  Sales Agreement
• Filed
  October 4th, 2021
• Company
  Metacrine, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

Metacrine, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with SVB Leerink LLC (the “Agent”), as follows:

METACRINE, INC. and , AS WARRANT AGENT FORM OF PREFERRED STOCK WARRANT AGREEMENT DATED AS OF [ ], 20 METACRINE, INC. FORM OF PREFERRED STOCK WARRANT AGREEMENT

Preferred Stock Warrant Agreement • October 4th, 2021 • Metacrine, Inc. • Pharmaceutical preparations • New York

• Contract Type
  Preferred Stock Warrant Agreement
• Filed
  October 4th, 2021
• Company
  Metacrine, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

PREFERRED STOCK WARRANT AGREEMENT (this “Agreement”), dated as of between METACRINE, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

METACRINE, INC. and , AS WARRANT AGENT FORM OF COMMON STOCK WARRANT AGREEMENT DATED AS OF [ ], 20 METACRINE, INC. FORM OF COMMON STOCK WARRANT AGREEMENT

Common Stock Warrant Agreement • October 4th, 2021 • Metacrine, Inc. • Pharmaceutical preparations • New York

• Contract Type
  Common Stock Warrant Agreement
• Filed
  October 4th, 2021
• Company
  Metacrine, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

COMMON STOCK WARRANT AGREEMENT (this “Agreement”), dated as of between METACRINE, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

METACRINE, INC. and , AS WARRANT AGENT FORM OF DEBT SECURITIES WARRANT AGREEMENT DATED AS OF [ ], 20 METACRINE, INC. FORM OF DEBT SECURITIES WARRANT AGREEMENT

Debt Securities Warrant Agreement • October 4th, 2021 • Metacrine, Inc. • Pharmaceutical preparations • New York

• Contract Type
  Debt Securities Warrant Agreement
• Filed
  October 4th, 2021
• Company
  Metacrine, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

DEBT SECURITIES WARRANT AGREEMENT (this “Agreement”), dated as of between METACRINE, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).