0001193125-24-180379 Sample Contracts

WARRANT AGENT AGREEMENT
Warrant Agent Agreement • July 17th, 2024 • Iterum Therapeutics PLC • Pharmaceutical preparations • New York

This WARRANT AGENT AGREEMENT (this “Agreement”) between Iterum Therapeutics plc, a public limited company incorporated under the laws of Ireland (registered number 563531) (the “Company”), Computershare Inc., a Delaware corporation (“Computershare”) and its affiliate Computershare Trust Company, N.A., a federally chartered trust company (“Trust Company”, and together with Computershare, collectively, the “Warrant Agent”), is dated as of _____, 2024.

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ITERUM THERAPEUTICS PLC. DEALER-MANAGER AGREEMENT
Dealer-Manager Agreement • July 17th, 2024 • Iterum Therapeutics PLC • Pharmaceutical preparations • New York

The following will confirm our agreement relating to the proposed rights offering (the “Rights Offering”) to be undertaken by Iterum Therapeutics PLC., an Irish public limited company (the “Company”), pursuant to which the Company will distribute to holders of record of (i) its ordinary shares, nominal value $0.01 per share (“Ordinary Shares”), and (ii) warrants that have contractual rights to participate in the proposed rights offering which have not otherwise been waived (each, an “eligible warrant” and collectively, the “Eligible Warrants”) subscription rights (the “Rights”) to subscribe for and purchase up to an aggregate of 8,503,800 units (the “Units”), each whole Unit consisting of (a) one Ordinary Share (the “Rights Shares”), (b) warrants to purchase up to 4,251,900 ordinary shares, at an exercise price of $1.21 per whole Ordinary Share from the date of issuance through its expiration one year from the date of issuance (the “1-Year Warrants”) and (c) warrants to purchase up to

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