0001193805-22-001449 Sample Contracts

DEPOSIT AGREEMENT
Deposit Agreement • October 24th, 2022 • Citibank,N.A./ADR • Services-medical laboratories • New York

DEPOSIT AGREEMENT, dated as of February 3, 2020, by and among (i) ANPAC BIO-MEDICAL SCIENCE CO., LTD., a business company limited by shares incorporated in the British Virgin Islands, and its successors (the “Company”), (ii) CITIBANK, N.A., a national banking association organized under the laws of the United States of America (“Citibank”) acting in its capacity as depositary, and any successor depositary hereunder (Citibank in such capacity, the “Depositary”), and (iii) all Holders and Beneficial Owners of American Depositary Shares issued hereunder (all such capitalized terms as hereinafter defined).

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CUSTODIAL SERVICES AGREEMENT FOR STRUCTURAL SAFEKEEPING ACCOUNT AT CITIBANK, N.A. – NEW YORK BRANCH, AS CUSTODIAN, FOR ANPAC BIO-MEDICAL SCIENCE CO., LTD., AS CLIENT dated as of July 30, 2020
Custodial Services Agreement • October 24th, 2022 • Citibank,N.A./ADR • Services-medical laboratories • New York

THIS CUSTODIAL SERVICES AGREEMENT FOR STRUCTURAL SAFEKEEPNG ACCOUNT, dated as of July 30, 2020, by and between Citibank, N.A. – NY Branch, as Custodian (the “Custodian”), and ANPAC BIO-MEDICAL SCIENCE CO., LTD., as client (the “Client”).

Citibank, N.A. – ADR Depositary Re: ANPAC BIO-MEDICAL SCIENCE CO., LTD. – Convertible Debenture Due 2022 Ladies & Gentlemen,
Citibank,N.A./ADR • October 24th, 2022 • Services-medical laboratories • New York

We refer to the Deposit Agreement, dated as of February 3, 2020, by and among Anpac Bio-Medical Science Co. Ltd. (the “Company”), Citibank, N.A., as depositary (the “Depositary”), and all Holders and Beneficial Owners of American Depositary Shares (“ADSs”) issued thereunder (as so amended and supplemented, the “ADS Deposit Agreement”). Terms used, but not otherwise defined, herein shall have the meaning ascribed to them in the ADS Deposit Agreement.

Citibank, N.A. – ADR Depositary Re: ANPAC BIO-MEDICAL SCIENCE CO., LTD. – Convertible Notes Due 2022 Ladies & Gentlemen,
Letter Agreement • October 24th, 2022 • Citibank,N.A./ADR • Services-medical laboratories • New York

We refer to the Deposit Agreement, dated as of February 3, 2020, by and among Anpac Bio-Medical Science Co. Ltd. (the “Company”), Citibank, N.A., as depositary (the “Depositary”), and all Holders and Beneficial Owners of American Depositary Shares (“ADSs”) issued thereunder (as so amended and supplemented, the “ADS Deposit Agreement”). Terms used, but not otherwise defined, herein shall have the meaning ascribed to them in the ADS Deposit Agreement.

Re: ANPAC BIO-MEDICAL SCIENCE CO., LTD. – Convertible Notes Due July 22, 2022
Note Conversion Letter Agreement • October 24th, 2022 • Citibank,N.A./ADR • Services-medical laboratories

We refer to the Deposit Agreement, dated as of February 3, 2020, by and among Anpac Bio-Medical Science Co. Ltd. (the “Company”), Citibank, N.A., as depositary (the “Depositary”), and all Holders and Beneficial Owners of American Depositary Shares (“ADSs”) issued thereunder, as amended and supplemented from time to time (as so amended and supplemented, the “ADS Deposit Agreement”). Terms used, but not otherwise defined, herein shall have the meaning ascribed to them in the ADS Deposit Agreement.

Citibank, N.A. – ADR Depositary Re: ANPAC BIO-MEDICAL SCIENCE CO., LTD. – Convertible Notes Due 2021 Ladies & Gentlemen,
Citibank,N.A./ADR • October 24th, 2022 • Services-medical laboratories • New York

We refer to the Deposit Agreement, dated as of February 3, 2020, by and among Anpac Bio-Medical Science Co. Ltd. (the “Company”), Citibank, N.A., as depositary (the “Depositary”), and all Holders and Beneficial Owners of American Depositary Shares (“ADSs”) issued thereunder (as so amended and supplemented, the “ADS Deposit Agreement”). Terms used, but not otherwise defined, herein shall have the meaning ascribed to them in the ADS Deposit Agreement.

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