0001564590-17-009841 Sample Contracts

RESEARCH AND LICENSE AGREEMENT between
Research and License Agreement • May 9th, 2017 • Akebia Therapeutics, Inc. • Pharmaceutical preparations • New York

This RESEARCH AND LICENSE AGREEMENT (the “Agreement”) is made and entered into effective as of February 9, 2017 (the “Effective Date”), by and between Akebia Therapeutics, Inc., a company organized and existing under the laws of the State of Delaware having a business address at 245 First Street, Suite 1100, Cambridge, MA 02142 (“Licensee”), and Janssen Pharmaceutica NV, a company organized and existing under the laws of Belgium having a business address at Turnhoutseweg 30, 2340 Beerse, Belgium (“Janssen”). Janssen and Licensee are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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COMMON STOCK PURCHASE WARRANT AKEBIA THERAPEUTICS, INC.
Common Stock Purchase Warrant • May 9th, 2017 • Akebia Therapeutics, Inc. • Pharmaceutical preparations • New York

THIS COMMON STOCK PURCHASE WARRANT (this “Warrant”) certifies that Johnson & Johnson Innovation -- JJDC, Inc. or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Issuance Date”) and on or prior to the close of business on the fifth anniversary of the Initial Issuance Date (the “Termination Date”) but not thereafter, to subscribe for and purchase from Akebia Therapeutics, Inc., a Delaware corporation (the “Company”), up to 509,611 shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b). The Company and the Holder are sometimes referred to herein individually as a “Party” and collectively as the “Parties”.

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