0001564590-19-009156 Sample Contracts

Re: Amended and Restated Employment Agreement
Employment Agreement • March 25th, 2019 • Xenon Pharmaceuticals Inc. • Pharmaceutical preparations

We are pleased to offer you this Amended and Restated Employment Agreement which replaces and supersedes your earlier Employment Agreement. You will be credited for all purposes with your service to the Company back to your start date of October 21, 2013. As of March 19, 2019 (the “Effective Date”), you will continue to be engaged by the Company in the full-time position of President & CFO.

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Re: Amended and Restated Employment Agreement (U.S. Executive)
Employment Agreement • March 25th, 2019 • Xenon Pharmaceuticals Inc. • Pharmaceutical preparations • Massachusetts

We are pleased to offer you this Amended and Restated Employment Agreement which replaces and supersedes your earlier Offer of Employment (the “Prior Agreement”) dated [DATE] with Xenon Pharmaceuticals USA Inc. (the “Company”), a wholly-owned subsidiary of Xenon Pharmaceuticals Inc. (the “Parent”). You will be credited for all purposes with your service to the Company back to your start date of [DATE]. As of [DATE] (the “Effective Date”), you will continue to be engaged by the Company in the full-time position of [TITLE]. Subject to Sections L through P below, the Company agrees to employ you, and you agree to serve the Company, on an “at-will” basis, which means that either the Company or you may terminate your employment with the Company at any time and for any or no reason, in accordance with the terms of this agreement (the “Agreement”).

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