KARYOPHARM THERAPEUTICS INC. NONSTATUTORY STOCK OPTION AGREEMENT Inducement GrantNonstatutory Stock Option Agreement • November 2nd, 2020 • Karyopharm Therapeutics Inc. • Pharmaceutical preparations • Delaware
This option satisfies in full all commitments that the Company has to the Participant with respect to the issuance of stock, stock options or other equity securities.
Restricted Stock Unit Agreement (Time Vested) 2013 Stock Incentive Plan NOTICE OF GRANTRestricted Stock Unit Agreement • November 2nd, 2020 • Karyopharm Therapeutics Inc. • Pharmaceutical preparations • Delaware
This Restricted Stock Unit Agreement (this “Agreement”) is made as of the Agreement Date between Karyopharm Therapeutics Inc. (the “Company”), a Delaware corporation, and the Participant.
October 1, 2020 Ran Frankel Dear Ran:Karyopharm Therapeutics Inc. • November 2nd, 2020 • Pharmaceutical preparations
You and Karyopharm Therapeutics Inc. (the “Company”) are parties to a letter agreement dated June 7, 2015, as amended on October 4, 2016, related to your employment as the Chief Development Operations Officer of the Company (the “Letter Agreement”). This letter is to inform you that, effective August 28, 2020 the Compensation Committee of the Board of Directors of the Company approved certain enhanced severance benefits for you, as described below, in addition to the benefits you may be entitled to under the Letter Agreement. Except as specifically set forth below, the Letter Agreement remains in full force and effect, and no provisions thereof are amended except as set forth below. Capitalized terms used but not defined herein shall have the meaning set forth in the Letter Agreement.
KARYOPHARM THERAPEUTICS INC. INCENTIVE STOCK OPTION AGREEMENTIncentive Stock Option Agreement • November 2nd, 2020 • Karyopharm Therapeutics Inc. • Pharmaceutical preparations
This option satisfies in full all commitments that the Company has to the Participant with respect to the issuance of stock, stock options or other equity securities.
KARYOPHARM THERAPEUTICS INC. Nonstatutory STOCK OPTION AGREEMENTNonstatutory Stock Option Agreement • November 2nd, 2020 • Karyopharm Therapeutics Inc. • Pharmaceutical preparations
This option satisfies in full all commitments that the Company has to the Participant with respect to the issuance of stock, stock options or other equity securities.
FIFTH AMENDMENT TO LEASELease • November 2nd, 2020 • Karyopharm Therapeutics Inc. • Pharmaceutical preparations • Massachusetts
Quincy, Massachusetts 02169, and Karyopharm Therapeutics Inc. (“Tenant”), a Delaware corporation, with an address of 85 Wells Avenue, 2nd Floor, Newton, Massachusetts 02459.
Restricted Stock Unit Agreement (Time Vested)Karyopharm Therapeutics Inc. • November 2nd, 2020 • Pharmaceutical preparations
