LOAN AGREEMENT dated as of December 31, 2020 by and between R-BRIDGE HEALTHCARE CAYMAN AIV, L.P., as Lender, and PRTK SPV2 LLC, as BorrowerLoan Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
This LOAN AGREEMENT (this “Agreement”) dated as of December 31, 2020, is entered into by and between R-BRIDGE HEALTHCARE CAYMAN AIV, L.P., a Cayman Islands exempted limited partnership, as lender (“Lender”), and PRTK SPV2 LLC, a Delaware limited liability company, as borrower (“Borrower”). Capitalized terms not otherwise defined herein shall have the meanings set forth in, or by reference in, Article I below.
CONTRIBUTION AND SERVICING AGREEMENT dated as of December 31, 2020 by and between PARATEK PHARMACEUTICALS, INC., as Contributor, and PRTK SPV2 LLC, as CompanyContribution and Servicing Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
REVENUE INTEREST PURCHASE AGREEMENT dated as of December 31, 2020 by and between PARATEK PHARMACEUTICALS, INC., as Seller, and PRTK SPV2 LLC, as CompanyRevenue Interest Purchase Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED WITH [***], HAS BEEN OMITTED BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED.Manufacturing and Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Third Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Third Amendment”) is made as of July 28, 2020 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Paratek”) and CIPAN Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
FIRST AMENDMENT TO THE MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This First Amendment to the Manufacturing and Services Agreement (the “First Amendment”) is made as of September 4, 2020 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116, United States (“Paratek”) and Almac Pharma Services Limited, a company organized and existing under the laws of Northern Ireland with an address at Almac House, 20 Seagoe Industrial Estate, Craigavon, BT63 5QD, Northern Ireland (“Almac”) and together with Paratek, the “Parties”. Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
FOURTH AMENDMENT TO THE AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Fourth Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Fourth Amendment”) is made as of December 16, 2020 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Paratek”) and CIPAN- Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
AMENDMENT AGREEMENT ‑ AMENDMENT NO.3 TO THE PRODUCT AGREEMENT DATED JULY 28, 2017Master Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
AMENDMENT AGREEMENT – AMENDMENT NO. 2 TO THE PRODUCT AGREEMENT DATED JULY 28, 2017Amendment Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
SECOND AMENDMENT TO THE AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Second Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Second Amendment”) is made as of December 20, 2019 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Paratek”) and CIPAN-Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, n°42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED WITH [***], HAS BEEN OMITTED BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED.Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Second Amendment to the Manufacturing and Services Agreement (the “Second Amendment”) is made as of January 1, 2021 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116, United States (“Paratek”) and Almac Pharma Services Limited, a company organized and existing under the laws of Northern Ireland with an address at Almac House, 20 Seagoe Industrial Estate, Craigavon, BT63 5QD, Northern Ireland (“Almac”) and together with Paratek, the “Parties”. Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED WITH [***], HAS BEEN OMITTED BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED.And Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
THIS FIRST AMENDMENT (the “Amendment”) is made as of the 01 day of June, 2019 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a corporation existing under the laws of Delaware, with an address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Client”) and Patheon UK Limited, a corporation existing under the laws of England, with an address at Kingfisher Drive, Covingham, Swindon, SN3 5BZ, United Kingdom (“Patheon”), (collectively referred to herein with the Client as the “Parties” and each, a “Party”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
SECOND AMENDMENT OF MANUFACTURING AND SERVICES AGREEMENTAnd Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
THIS SECOND AMENDMENT (the “Second Amendment”) is made as of December 18, 2020 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a corporation existing under the laws of Delaware, with an address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Client”) and Patheon UK Limited, a corporation existing under the laws of England, with an address at Kingfisher Drive, Covingham, Swindon, SN3 5BZ, United Kingdom (“Patheon”), (collectively referred to herein with the Client as the “Parties” and each, a “Party”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
