AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • August 2nd, 2018 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
THIS AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENT (this “Agreement”) is made and entered into as of April 18, 2018 (the “Effective Date”), by and between Paratek Pharmaceuticals, Inc., a corporation organized and existing under the laws of Delaware, with an address at 75 Park Plaza, 4th Floor, Boston, Massachusetts 02116, United States (“Paratek”) and CIPAN ̵̶ Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and, collectively with Paratek, the “Parties”, and each, a “Party”).
MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • May 5th, 2017 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
THIS MANUFACTURING AND SERVICES AGREEMENT (this “Agreement”) is made and entered into as of December 30, 2016 (the “Effective Date”), by and between Paratek Pharmaceuticals, Inc., a corporation organized and existing under the laws of Delaware, with an address at 75 Park Plaza, 4th Floor, Boston, Massachusetts 02116, United States (“Paratek”), on the one hand, and Almac Pharma Services Limited, a company organized and existing under the laws of Northern Ireland with an address at Almac House, 20 Seagoe Industrial Estate, Craigavon, Northern Ireland, BT63 5QD (“Almac”), on the other hand. Paratek and Almac are collectively referred to herein as the “Parties”, and each, a “Party”.
CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED WITH [***], HAS BEEN OMITTED BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED.Manufacturing and Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Third Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Third Amendment”) is made as of July 28, 2020 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Paratek”) and CIPAN Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
FIRST AMENDMENT TO THE MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This First Amendment to the Manufacturing and Services Agreement (the “First Amendment”) is made as of September 4, 2020 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116, United States (“Paratek”) and Almac Pharma Services Limited, a company organized and existing under the laws of Northern Ireland with an address at Almac House, 20 Seagoe Industrial Estate, Craigavon, BT63 5QD, Northern Ireland (“Almac”) and together with Paratek, the “Parties”. Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
FOURTH AMENDMENT TO THE AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Fourth Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Fourth Amendment”) is made as of December 16, 2020 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Paratek”) and CIPAN- Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
THIRD AMENDMENT TO THE MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • March 16th, 2023 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Third Amendment to the Manufacturing and Services Agreement (the “Third Amendment”) is made as of October 15, 2022 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116, United States (“Paratek”) and Almac Pharma Services Limited, a company organized and existing under the laws of Northern Ireland with an address at Almac House, 20 Seagoe Industrial Estate, Craigavon, BT63 5QD, Northern Ireland (“Almac”) and together with Paratek, the “Parties”. Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
TREATS AS PRIVATE OR CONFIDENTIAL. SIXTH AMENDMENT TO THE AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • March 16th, 2023 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Sixth Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Sixth Amendment”) is made as of 2/23/2023 (the “Sixth Amendment Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 1000 First Avenue, Suite 200, King of Prussia, PA 19406 (“Paratek”) and CIPAN ̵̶ Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
FIRST AMENDMENT OF AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • March 6th, 2019 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
THIS FIRST AMENDMENT OF AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENT (the “Amendment”) is made as of February 18, 2019 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a corporation existing under the laws of Delaware, with an address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Paratek”) and CIPAN ̵̶ Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN”, collectively referred to herein with Paratek as the “Parties” and each, a “Party”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
SECOND AMENDMENT TO THE AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • January 4th, 2021 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Second Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Second Amendment”) is made as of December 20, 2019 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116 (“Paratek”) and CIPAN-Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, n°42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
FIFTH AMENDMENT TO THE AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENTManufacturing and Services Agreement • March 14th, 2022 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations
This Fifth Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Fifth Amendment”) is made as of January 11, 2022 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 1000 First Avenue, Suite 200, King of Prussia, PA 19406 (“Paratek”) and CIPAN ̵̶ Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.
1 EXHIBIT 10.1 MANUFACTURING AND SERVICES AGREEMENT AGREEMENT dated as of the 1st day of July 1996 by and between WMS INDUSTRIES INC. ("WMS"), a Delaware corporation with its principal place of business at 3401 North California Avenue, Chicago,...Manufacturing and Services Agreement • October 18th, 1996 • Midway Games Inc • Miscellaneous manufacturing industries • Illinois
