0001564590-21-055047 Sample Contracts

AMENDMENT NO. 2 TO 2009 LICENSE AGREEMENT
License Agreement • November 8th, 2021 • Reata Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

Amendment No. 2, dated as of August 17, 2021 (this “Amendment”), to the Reata Pharmaceuticals, Inc. - Dartmouth Exclusive License Agreement, effective December 16, 2009, as amended by the Amendment No. 1 to 2009 License Agreement dated as of July 9, 2012 (as so amended, the “License Agreement”), by and between Trustees of Dartmouth College (“DARTMOUTH”), said college being a non-profit educational and research institution existing under the laws of the State of New Hampshire, Hanover, New Hampshire 03755, and Reata Pharmaceuticals, Inc. (“REATA”), a Delaware corporation having a principal place of business located at 5320 Legacy Drive, Plano, Texas 75024.

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AMENDMENT NO. 2 TO 2004 LICENSE AGREEMENT
Exclusive Patent License Agreement • November 8th, 2021 • Reata Pharmaceuticals Inc • Pharmaceutical preparations • Texas

Amendment No. 2, dated as of August 17, 2021 (this “Amendment”), to the Exclusive Patent License Agreement, dated as of July 15, 2004, as amended by the Amendment effective as of April 11, 2007 and as further amended by the Amendment No. 1 to 2004 License Agreement dated as of July 9, 2012 (as so amended, excluding this Amendment, the “License Agreement”), by and among the Board of Regents (the “BOARD”) of The University of Texas System (the “SYSTEM”), an agency of the State of Texas, whose address is 201 West 7th Street, Austin, Texas 78701, on behalf of The University of Texas M. D. Anderson Cancer Center (“UTMDACC”), a component institution of the SYSTEM, Trustees of Dartmouth College (“DARTMOUTH”), a non-profit educational and research institution existing under the laws of the State of New Hampshire, and being located at Hanover, New Hampshire (BOARD, UTMDACC and DARTMOUTH collectively “LICENSORS”), and Reata Pharmaceuticals, Inc., a Delaware corporation and also formerly known as

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