0001571049-17-003302 Sample Contracts

FIFTH AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • April 10th, 2017 • Arqule Inc • Pharmaceutical preparations • Massachusetts

This Fifth Amendment to Employment Agreement (“Fifth Amendment”), effective as of April 4, 2017 (the “Effective Date”) is entered into by and between ArQule, Inc., a Delaware corporation (the “Company”) with its principal offices at One Wall Street, Burlington, Massachusetts 01803, and Peter Lawrence (“Executive”). The purpose of this Fifth Amendment is to amend the employment agreement dated as of April 13, 2006 between the Company and Executive, as previously amended (the “Employment Agreement”). Capitalized terms used but not defined in this Fifth Amendment shall have the meanings ascribed to them in the Employment Agreement.

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FOURTH AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • April 10th, 2017 • Arqule Inc • Pharmaceutical preparations • Massachusetts

This Fourth Amendment to Employment Agreement (“Fourth Amendment”), effective as of April 4, 2017 (the “Effective Date”) is entered into by and between ArQule, Inc., a Delaware corporation (the “Company”) with its principal offices at One Wall Street, Burlington, Massachusetts 01803, and Brian Schwartz (“Executive”). The purpose of this Fourth Amendment is to amend the employment agreement dated as of June 17, 2008 between the Company and Executive, as previously amended (the “Employment Agreement”). Capitalized terms used but not defined in this Fourth Amendment shall have the meanings ascribed to them in the Employment Agreement.

FOURTH AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • April 10th, 2017 • Arqule Inc • Pharmaceutical preparations • Massachusetts

This Fourth Amendment to Employment Agreement (“Fourth Amendment”), effective as of April 4, 2017 (the “Effective Date”) is entered into by and between ArQule, Inc., a Delaware corporation (the “Company”) with its principal offices at One Wall Street, Burlington, Massachusetts 01803, and Paolo Pucci (“Executive”). The purpose of this Fourth Amendment is to amend the employment agreement dated as of April 15, 2008 between the Company and Executive, as previously amended (the “Employment Agreement”). Capitalized terms used but not defined in this Fourth Amendment shall have the meanings ascribed to them in the Employment Agreement.

ARQULE, INC. PERFORMANCE STOCK OPTION AGREEMENT
Performance Stock Option Agreement • April 10th, 2017 • Arqule Inc • Pharmaceutical preparations • Massachusetts

THIS PERFORMANCE STOCK OPTION AGREEMENT (the “Option Agreement”) is dated as of April 5, 2017 (the “Grant Date”) by and between ArQule, Inc., a Delaware Company (the “Company”), and ____________________ (the “Participant”). Capitalized terms used herein and not otherwise defined shall have the meaning assigned to such terms in the ArQule, Inc. 2014 Equity Incentives Plan (the “Plan”).

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