SIXTH AMENDMENT TO LEASELease • February 25th, 2021 • Akebia Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts
This SIXTH AMENDMENT TO LEASE (this “Amendment”) is entered into as of November 30, 2020 (the “Effective Date”), by and between CLPF-CAMBRIDGE SCIENCE CENTER, LLC, a Delaware limited liability company (“Landlord”), and AKEBIA THERAPEUTICS, INC., a Delaware corporation (“Tenant”).
AMENDMENT NO. 1 TO MASTER MANUFACTURING SERVICES AND SUPPLY AGREEMENTMaster Manufacturing Services and Supply Agreement • February 25th, 2021 • Akebia Therapeutics, Inc. • Pharmaceutical preparations
This Amendment No. 1 to Master Manufacturing Services and Supply Agreement (“Amendment No. 1”) is made effective and entered into on December 21, 2020 (the “Amendment Effective Date”) by and between Siegfried Evionnaz SA, with principal offices located at Route du Simplon 1, 36, 1902 Evionnaz, Switzerland (together with its Affiliates and subsidiaries “Vendor”); and Keryx Biopharmaceuticals, Inc., with its offices at 245 First Street, Cambridge, Massachusetts, USA 02142 (“Keryx”).
Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. AMENDMENT NO. 3 TO MASTER...Services and Supply Agreement • February 25th, 2021 • Akebia Therapeutics, Inc. • Pharmaceutical preparations
This Amendment No. 3 to Master Manufacturing Services and Supply Agreement (“Amendment No. 3”) is made effective and entered into on February 11, 2021 (the “Amendment Effective Date”) by and between Siegfried Evionnaz SA, with principal offices located at Route du Simplon 1, 36, 1902 Evionnaz, Switzerland (together with its Affiliates and subsidiaries “Vendor”); and Keryx Biopharmaceuticals, Inc., with its offices at 245 First Street, Cambridge, Massachusetts, USA 02142 (“Keryx”).
AMENDMENT NO. 2 TO MASTER MANUFACTURING SERVICES AND SUPPLY AGREEMENTMaster Manufacturing Services and Supply Agreement • February 25th, 2021 • Akebia Therapeutics, Inc. • Pharmaceutical preparations
This Amendment No. 2 to Master Manufacturing Services and Supply Agreement (“Amendment No. 2”) is made effective and entered into on January 29, 2021 (the “Amendment Effective Date”) by and between Siegfried Evionnaz SA, with principal offices located at Route du Simplon 1, 36, 1902 Evionnaz, Switzerland (together with its Affiliates and subsidiaries “Vendor”); and Keryx Biopharmaceuticals, Inc., with its offices at 245 First Street, Cambridge, Massachusetts, USA 02142 (“Keryx”).
