0001628280-23-016258 Sample Contracts

Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. AMENDMENT NO. 5 TO...
Master Manufacturing Services and Supply Agreement • May 8th, 2023 • Akebia Therapeutics, Inc. • Pharmaceutical preparations

This Amendment No. 5 to Master Manufacturing Services and Supply Agreement (“Amendment No. 5”) is made effective and entered into on February 28, 2023 (the “Amendment No. 5 Effective Date”) by and between Siegfried Evionnaz SA, with principal offices located at Route du Simplon 1, 36, 1902 Evionnaz, Switzerland (together with its Affiliates and subsidiaries “Vendor”); and Keryx Biopharmaceuticals, Inc., with its offices at 245 First Street, Cambridge, Massachusetts, USA 02142 (“Keryx”).

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OFFICER STOCK APPRECIATION RIGHTS AWARD granted under the AKEBIA THERAPEUTICS, INC. STOCK APPRECIATION RIGHTS AGREEMENT
Stock Appreciation Rights Agreement • May 8th, 2023 • Akebia Therapeutics, Inc. • Pharmaceutical preparations

This agreement (the “Agreement”) evidences a SAR granted by Akebia Therapeutics, Inc. (the “Company”) to the undersigned (the “Grantee”), pursuant to and subject to the terms of the Akebia Therapeutics, Inc. 2014 Incentive Plan, as amended (the “Plan”).

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