0001694665-21-000066 Sample Contracts

April 9, 2021
Letter Agreement • April 29th, 2021 • Evelo Biosciences, Inc. • Pharmaceutical preparations

Reference is made to my letter dated as of September 16, 2019 addressed to you concerning your compensation for serving as the Chair of the Board of Directors of Evelo Biosciences, Inc. (as previously amended, the “Letter Agreement”). This letter memorializes our recent discussion concerning an amendment to your compensation, and will become effective upon your signature below (the “Amendment”).

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Evelo Biosciences, Inc. Amendment No. 2 to Consulting Agreement
Consulting Agreement • April 29th, 2021 • Evelo Biosciences, Inc. • Pharmaceutical preparations

This Amendment to that certain Consulting Agreement dated as of September 16, 2019 (as previously amended, the “Agreement”) is entered into by and between Evelo Biosciences, Inc., a Delaware corporation with a place of business located at 620 Memorial Drive, Cambridge, Massachusetts 02139, USA (the “Company”), and David Epstein, an individual residing at [***] (the “Consultant”).

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