Addendum to Trademark License and Supply Agreement Sample Contracts

Re: Addendum to Trademark License and Supply Agreement dated May 28, 2014 Dear Stephen,
Addendum to Trademark License and Supply Agreement • November 6th, 2015 • Retrophin, Inc. • Pharmaceutical preparations

As you are aware, Retrophin has requested that Mission Pharmacal build a significant safety stock of tiopronin, the active pharmaceutical ingredient (API) in THIOLA. The safety stock is requested to insure that there is no interruption in the supply of THIOLA and to prepare for a potential development project, whereby THIOLA may be reformulated. Due to the financial burden of purchasing such large quantities of tiopronin prior to firm production orders, Mission is requesting immediate reimbursement for the safety stock purchases.

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