To: Citibank, N.A. – ADR Depositary 388 Greenwich Street, 14th Floor New York, NY 10013 Attention: Depositary Receipt Department Re: Amarin Corporation plc – ADSs (CUSIP No.: 023111206) & Restricted ADSs (CUSIP No.: 0231119L3)Ads Letter Agreement • November 29th, 2018 • Citibank,N.A./ADR • Pharmaceutical preparations • New York
Contract Type FiledNovember 29th, 2018 Company Industry JurisdictionReference is made to the Amended and Restated Deposit Agreement, dated as of November 4, 2011, by and among Amarin Corporation plc, a company organized under the laws of England and Wales (the "Company"), Citibank, N.A., as Depositary (the "Depositary"), and all Holders and Beneficial Owners of American Depositary Shares ("ADSs") issued thereunder (the "Deposit Agreement"). All capitalized terms used, but not otherwise defined, herein shall have the meaning assigned thereto in the Deposit Agreement.