Agreement Not to Tender Sample Contracts

Re: Agreement Not to Tender
Agreement Not to Tender • January 2nd, 2018 • Cryoport, Inc. • Arrangement of transportation of freight & cargo • Nevada

This letter agreement is being delivered in connection with the offer by Cryoport, Inc., a Nevada corporation (the “Company”), to holders of the Company’s outstanding warrants to purchase one share of common stock at an exercise price of $3.57 per share (the “Original Warrants”) the opportunity to exchange up to 2,000,000 of such Original Warrants for an equal number of warrants to purchase one share of common stock at an exercise price of $3.00 per share (the “New Warrants”), conditioned upon the immediate exercise of such New Warrants. The Offer is being made upon the terms and subject to the conditions set forth in the offer letter/prospectus, dated on or about January 2, 2018.

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March 3, 2016 Cryoport, Inc. 17305 Daimler Street Irvine, CA 92614 Re: Agreement Not to Tender Ladies and Gentlemen:
Agreement Not to Tender • March 3rd, 2016 • Cryoport, Inc. • Plastics foam products • Nevada

Reference is made to Cryoport, Inc.’s (the “Company”) proposed offering to amend (the “Tender Offer”), upon the terms and subject to the conditions set forth in that certain Offer to Amend and Exercise Warrants to Purchase Common Stock, dated March 3, 2016, certain outstanding warrants to purchase common stock of the Company, including warrants (the “Warrants”) held by the undersigned as described below.

Re: Agreement Not to Tender
Agreement Not to Tender • January 2nd, 2018 • Cryoport, Inc. • Arrangement of transportation of freight & cargo • Nevada

This letter agreement is being delivered in connection with the offer by Cryoport, Inc., a Nevada corporation (the “Company”), to holders of the Company’s outstanding warrants to purchase one share of common stock at an exercise price of $3.57 per share (the “Original Warrants”) the opportunity to exchange up to 2,000,000 of such Original Warrants for an equal number of warrants to purchase one share of common stock at an exercise price of $3.00 per share (the “New Warrants”), conditioned upon the immediate exercise of such New Warrants. The Offer is being made upon the terms and subject to the conditions set forth in the offer letter/prospectus, dated on or about January 2, 2018.

Re: Agreement Not to Tender
Agreement Not to Tender • August 11th, 2016 • Cryoport, Inc. • Plastics foam products • Nevada

This letter agreement is being delivered in connection with the offer by Cryoport, Inc., a Nevada corporation (the “Company”), to holders of the Company’s outstanding warrants to purchase one share of common stock at an exercise price of $3.57 per share (the “Original Warrants”) the opportunity to exchange such Original Warrants for (1) an equal number of warrants to purchase one share of common stock at an exercise price of $1.50 per share (the “New Warrants”), conditioned upon the immediate exercise of such New Warrants, and (ii) one warrant to purchase one share of common stock at an exercise price of $3.00 per share for every four New Warrants exercised (the “Supplemental Warrants”). The Offer is being made upon the terms and subject to the conditions set forth in the offer letter/prospectus, dated August 11, 2016.

Re: Agreement Not to Tender
Agreement Not to Tender • August 11th, 2016 • Cryoport, Inc. • Plastics foam products • Nevada

This letter agreement is being delivered in connection with the offer by Cryoport, Inc., a Nevada corporation (the “Company”), to holders of the Company’s outstanding warrants to purchase one share of common stock at an exercise price of $3.57 per share (the “Original Warrants”) the opportunity to exchange such Original Warrants for (1) an equal number of warrants to purchase one share of common stock at an exercise price of $1.50 per share (the “New Warrants”), conditioned upon the immediate exercise of such New Warrants, and (ii) one warrant to purchase one share of common stock at an exercise price of $3.00 per share for every four New Warrants exercised (the “Supplemental Warrants”). The Offer is being made upon the terms and subject to the conditions set forth in the offer letter/prospectus, dated August 11, 2016.

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