EXHIBIT 10.46 [***] CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY BRACKETS, HAS BEEN OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934, AS...Collaboration and Facilities Agreement • February 16th, 2005 • Cytokinetics Inc • Pharmaceutical preparations • California
Contract Type FiledFebruary 16th, 2005 Company Industry Jurisdiction
SECOND AMENDMENT TO COLLABORATION AND FACILITIES AGREEMENTCollaboration and Facilities Agreement • March 22nd, 2006 • Cytokinetics Inc • Pharmaceutical preparations
Contract Type FiledMarch 22nd, 2006 Company IndustryThis SECOND AMENDMENT (“Second Amendment”) is hereby entered into as of January 1, 2006 (the “Second Amendment Effective Date”), by and between Portola Pharmaceuticals, Inc. (“Portola”) and Cytokinetics, Inc. (“Cytokinetics”) (collectively, the “Parties”). Terms used in this Second Amendment and not otherwise defined herein shall have the meanings given to them in the Agreement (as defined below).
FIRST AMENDMENT TO COLLABORATION AND FACILITIES AGREEMENTCollaboration and Facilities Agreement • May 12th, 2005 • Cytokinetics Inc • Pharmaceutical preparations
Contract Type FiledMay 12th, 2005 Company IndustryThis FIRST AMENDMENT (“First Amendment”) is hereby entered into as of March 24, 2005 (the “First Amendment Effective Date”), by and between Portola Pharmaceuticals, Inc. (“Portola”) and Cytokinetics, Inc. (“Cytokinetics”) (collectively, the “Parties”). Terms used in this First Amendment and not otherwise defined herein shall have the meanings given to them in the Agreement (as defined below).