Collaboration and Promotion Agreement Sample Contracts

ARTICLE 1 DEFINITIONS
Collaboration and Promotion Agreement • March 1st, 2005 • Aspreva Pharmaceuticals CORP • Pharmaceutical preparations • New York
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William M. Burns F. Hoffmann-La Roche Ltd Grenzacherstrasse 124 CH-4070 Basel, Switzerland
Collaboration and Promotion Agreement • November 6th, 2007 • Aspreva Pharmaceuticals CORP • Pharmaceutical preparations

As a follow up to our recent discussions with you and your team regarding our CellCept® Collaboration and Promotion Agreement dated July 18, 2003, as amended (“Collaboration Agreement”), this letter (“Letter Agreement”) sets forth certain understandings and agreements reached by Aspreva and Roche with respect to activities undertaken by Roche to develop and commercialize CellCept for autoimmune indications (“ROW Activities”). The ROW Activities consist of the following:

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