Collaboration, License and Supply Sample Contracts

SECOND AMENDMENT TO COLLABORATION, LICENSE AND SUPPLY AGREEMENT
Collaboration, License and Supply • March 13th, 2015 • Alexza Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This SECOND AMENDMENT TO THE COLLABORATION, LICENSE AND SUPPLY AGREEMENT (the “Second Amendment”) is effective as of 6th November, 2013 (the “Second Amendment Effective Date”) by and between ALEXZA PHARMACEUTICALS, INC., a company organized under the laws of the State of Delaware, United States (“Alexza”), and having a principal place of business at 2091 Stierlin Court, Mountain View, CA 94043, United States, and GRUPO FERRER INTERNACIONAL, S.A., a company organized under the laws of Spain (“Ferrer”), having its registered office at Av. Diagonal 549, E-08029 Barcelona, Spain.

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