Collaboration Research and License Agreement Sample Contracts

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Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. COLLABORATION, RESEARCH AND LICENSE AGREEMENT BY AND BETWEEN PROCTER & GAMBLE COMPANY AND CURIS, INC. September 18, 2005...
Collaboration, Research and License Agreement • November 14th, 2005 • Curis Inc • Biological products, (no disgnostic substances) • New York

THIS COLLABORATION, RESEARCH AND LICENSE AGREEMENT (the “Agreement”) is made and entered into as of September 18, 2005 (the “Effective Date”), by and between PROCTER & GAMBLE COMPANY, an Ohio corporation, and its Affiliates (collectively, “P&G”), with a place of business at Health Care Research Center, 8700 Mason-Montgomery Road, Mason, Ohio 45040, and CURIS, INC., a Delaware corporation (“Curis”), with a place of business at 61 Moulton Street, Cambridge, Massachusetts 02138.

FIRST AMENDMENT TO COLLABORATION RESEARCH AND LICENSE AGREEMENT
Collaboration Research and License Agreement • November 5th, 2010 • Isis Pharmaceuticals Inc • Pharmaceutical preparations

THIS FIRST AMENDMENT TO COLLABORATION AND LICENSE AGREEMENT (the “Amendment”) is made and entered into effective as of July 27, 2010 (the “First Amendment Effective Date”) by and between Bristol-Myers Squibb Company, a Delaware corporation (“BMS”) and Isis Pharmaceuticals, Inc., a Delaware Corporation (“Isis”).

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