Contract to Supply Active Ingredients Sample Contracts

AMENDMENT NO. 1 TO CONTRACT TO SUPPLY ACTIVE INGREDIENTS
Contract to Supply Active Ingredients • March 31st, 2008 • Gentium S.p.A. • Pharmaceutical preparations

This Amendment No. 1 (this “Amendment”) to the Contract to Supply Active Ingredients is effective as of December 7, 2007 by and between Sirton Pharmaceuticals S.p.A. (“Sirton”) and Gentium S.p.A. (“Gentium”).

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