Cytokinetics, Incorporated Sample Contracts

CYTOKINETICS, INCORPORATED
Cytokinetics, Incorporated • December 2nd, 2011 • Cytokinetics Inc • Pharmaceutical preparations

Unless otherwise defined herein, the terms defined in the Cytokinetics, Incorporated 2004 Equity Incentive Plan (the “Plan”) shall have the same defined meanings in this Restricted Stock Unit Award Agreement (the “Agreement”).

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CYTOKINETICS, INCORPORATED and U.S. BANK NATIONAL ASSOCIATION as Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of November 13, 2019 4.00% Convertible Senior Notes due 2026
Cytokinetics, Incorporated • November 13th, 2019 • Cytokinetics Inc • Pharmaceutical preparations • New York

THIS SUPPLEMENTAL INDENTURE, dated as of November 13, 2019 (the “Supplemental Indenture”), to the Indenture, dated as of November 13, 2019 (the “Base Indenture” and, as amended, modified and supplemented by this Supplemental Indenture, the “Indenture”), between Cytokinetics, Incorporated, a Delaware corporation, as issuer (the “Company”) and U.S. Bank National Association, as trustee (the “Trustee”).

CYTOKINETICS, INCORPORATED COMMON STOCK OPTION PURCHASE AGREEMENT
Cytokinetics, Incorporated • August 9th, 2024 • Cytokinetics Inc • Pharmaceutical preparations • New York

THIS COMMON STOCK OPTION AND PURCHASE AGREEMENT (the “Agreement”) is made as of May 22, 2024 (the “Execution Date”) by and between Cytokinetics, Incorporated, a Delaware corporation (the “Company”), and Royalty Pharma Investments 2019 ICAV, an Irish collective asset-management vehicle (the “Investor”). Capitalized terms used but not defined herein shall have the meanings ascribed thereto in the CK-586 Purchase Agreement (defined below).

CYTOKINETICS, INCORPORATED and U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION as Trustee INDENTURE Dated as of July 6, 2022 3.50% Convertible Senior Notes due 2027
Cytokinetics, Incorporated • July 6th, 2022 • Cytokinetics Inc • Pharmaceutical preparations • New York

INDENTURE, dated as of July 6, 2022, between Cytokinetics, Incorporated, a Delaware corporation, as issuer (the “Company”), and U.S. Bank Trust Company, National Association, as trustee (the “Trustee”).

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