Distribution, License And Sample Contracts

FIRST AMENDMENT TO DISTRIBUTION, LICENSE AND SUPPLY AGREEMENTentered into as of the 22ndday of June, 2016 (the "First Amendment") BETWEEN: KNIGHT THERAPEUTICS INC., a corporation

Distribution, License And • July 14th, 2016 • Ember Therapeutics, Inc. - Ny • Pharmaceutical preparations • New York

• Contract Type
  Distribution, License And
• Filed
  July 14th, 2016
• Company
  Ember Therapeutics, Inc. - Ny
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

WHEREAS Ember and Knight are parties of a certain Distribution, License and Supply Agreement (the "Distribution Agreement"), made as of the 3rd day of August, 2015.