Distribution, Patent & Trademark License, Marketing and Supply Agreement Sample Contracts

RECITALS
Distribution, Patent & Trademark License, Marketing and Supply Agreement • November 4th, 2002 • Kos Pharmaceuticals Inc • Pharmaceutical preparations • New York
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CONFIDENTIAL MATERIAL OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. ASTERISKS DENOTE SUCH OMISSIONS. AMENDMENT NO. 2 TO DISTRIBUTION, PATENT & TRADEMARK LICENSE, MARKETING AND SUPPLY AGREEMENT
Distribution, Patent & Trademark License, Marketing and Supply Agreement • November 9th, 2006 • Kos Pharmaceuticals Inc • Pharmaceutical preparations

This Amendment Agreement (this “Amendment No. 2”) is entered into as of the 18th day of August 2006, by and between Kos Pharmaceuticals, Inc., a Florida corporation (“Kos”), and Merck KGaA, an entity organized under German law and registered in the commercial registry of the local court of Darmstadt under HRB 6164 (“Merck”).

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