First Amendment to Offer of Employment Sample Contracts

December 31, 2008 Keith Katkin c/o Avanir Pharmaceuticals 101 Enterprise, Suite 300 Aliso Viejo, CA 92656 Re: First Amendment to Offer of Employment Dear Keith:
First Amendment to Offer of Employment • December 8th, 2010 • Avanir Pharmaceuticals, Inc. • Pharmaceutical preparations

This letter amends the terms of the Offer of Employment (the “Agreement”) dated as of March 13, 2007, by and between Avanir Pharmaceuticals (“Avanir”) and you as set forth below. Capitalized terms not defined herein shall have the meaning specified in the Agreement.

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December 26, 2008 Luke Seikkula [Address] Re: First Amendment to Offer of Employment Dear Luke:
First Amendment to Offer of Employment • March 31st, 2009 • La Jolla Pharmaceutical Co • Biological products, (no disgnostic substances)

This letter amends the terms of the Offer of Employment (the “Agreement”) dated as of March 4, 2008, by and between La Jolla Pharmaceutical Company (“LJPC”) and you as set forth below. Capitalized terms not defined herein shall have the meaning specified in the Agreement.

December 26, 2008 Vickie Motte [Address] Re: First Amendment to Offer of Employment Dear Vickie:
First Amendment to Offer of Employment • March 31st, 2009 • La Jolla Pharmaceutical Co • Biological products, (no disgnostic substances)

This letter amends the terms of the Offer of Employment (the “Agreement”) dated as of September 19, 2008, by and between La Jolla Pharmaceutical Company (“LJPC”) and you as set forth below. Capitalized terms not defined herein shall have the meaning specified in the Agreement.

December 29, 2008 Lisa Koch-Hulle [Address] Re: First Amendment to Offer of Employment Dear Lisa:
First Amendment to Offer of Employment • March 31st, 2009 • La Jolla Pharmaceutical Co • Biological products, (no disgnostic substances)

This letter amends the terms of the Offer of Employment (the “Agreement”) dated as of March 4, 2008, by and between La Jolla Pharmaceutical Company (“LJPC”) and you as set forth below. Capitalized terms not defined herein shall have the meaning specified in the Agreement.

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