Lease and Agreement of Lease Sample Contracts

EXHIBIT 10.48 LEASE AND AGREEMENT OF LEASE
Lease and Agreement of Lease • March 12th, 1999 • Techniclone Corp/De/ • In vitro & in vivo diagnostic substances • California
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FIRST AMENDMENT TO LEASE AND AGREEMENT OF LEASE
Lease and Agreement of Lease • December 23rd, 2005 • Peregrine Pharmaceuticals Inc • In vitro & in vivo diagnostic substances

THIS FIRST AMENDMENT TO LEASE AND AGREEMENT OF LEASE (this "First Amendment") is made and entered into as of December 22, 2005 (the "Effective Date") by and between TNCA, LLC, a Delaware limited liability company ("Landlord") and PEREGRINE PHARMACEUTICALS, INC., a Delaware corporation (successor-in-interest to Techniclone Corporation, a Delaware corporation) ("Tenant").

Between TVCA, LLC a Delaware limited liability company as Landlord and TELEVIDEO, INC., a Delaware corporation as Tenant
Lease and Agreement of Lease • January 12th, 1999 • Televideo Systems Inc • Computer terminals • California
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