Metabolic Disorder Collaboration Agreement Sample Contracts

November 11, 2005
Metabolic Disorder Collaboration Agreement • March 14th, 2006 • Curagen Corp • Services-commercial physical & biological research

Reference is made to the Metabolic Disorder Collaboration Agreement dated January 12, 2001 between Bayer Corporation and CuraGen Corporation (as previously amended, the “Agreement”). Terms which are defined in the Agreement are used herein as so defined. This letter will set forth our agreement with respect to an amendment of the Agreement.

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May 30, 2006 CuraGen Corporation Branford, CT 06405 Attention: Executive Vice President, Business Development
Metabolic Disorder Collaboration Agreement • August 9th, 2006 • Curagen Corp • Services-commercial physical & biological research

Reference is made to the Metabolic Disorder Collaboration Agreement dated January 12, 2001 between Bayer Corporation and CuraGen Corporation (as previously amended, the “Agreement”). Terms which are defined in the Agreement are used herein as so defined. This letter will set forth our agreement with respect to the closing of the Qualified Target Production Phase of the Agreement and addresses issues not previously contemplated in the Agreement with respect to such closing.

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Metabolic Disorder Collaboration Agreement • March 28th, 2001 • Curagen Corp • Services-commercial physical & biological research • Delaware
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