Pharmaceutical Development Agreement Sample Contracts

AMENDMENT N°2 TO PHARMACEUTICAL DEVELOPMENT* AGREEMENT
Pharmaceutical Development Agreement • November 9th, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

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PHARMACEUTICAL DEVELOPMENT AGREEMENT TO DEVELOP A MULTIDOSE INJECTION FOR BIM 44058*
Pharmaceutical Development Agreement • September 30th, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation with its principal office at Beaufour Ipsen Industrie S.A.S, rue d’Ethe Virton, 28100, France (“Ipsen”).

AMENDMENT N°1 TO PHARMACEUTICAL DEVELOPMENT* AGREEMENT
Pharmaceutical Development Agreement • November 8th, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

AMENDMENT N°1 TO PHARMACEUTICAL DEVELOPMENT* AGREEMENT
Pharmaceutical Development Agreement • September 30th, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

PHARMACEUTICAL DEVELOPMENT AGREEMENT TO DEVELOP A MULTIDOSE INJECTION FOR BIM 44058*
Pharmaceutical Development Agreement • October 24th, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation with its principal office at Beaufour Ipsen Industrie S.A.S, rue d’Ethe Virton, 28100, France (“Ipsen”).

AMENDMENT N°4 TO PHARMACEUTICAL DEVELOPMENT AGREEMENT
Pharmaceutical Development Agreement • December 21st, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

AMENDMENT N°3 TO PHARMACEUTICAL DEVELOPMENT AGREEMENT*
Pharmaceutical Development Agreement • May 23rd, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

AMENDMENT N°3 TO PHARMACEUTICAL DEVELOPMENT AGREEMENT*
Pharmaceutical Development Agreement • October 24th, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

AMENDMENT N°3 TO PHARMACEUTICAL DEVELOPMENT AGREEMENT*
Pharmaceutical Development Agreement • September 30th, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

AMENDMENT N°6 TO PHARMACEUTICAL DEVELOPMENT AGREEMENT
Pharmaceutical Development Agreement • November 5th, 2015 • Radius Health, Inc. • Pharmaceutical preparations • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Joel Richard, Senior Vice-President, Peptides Development and CMC Dreux,

AMENDMENT N°1 TO PHARMACEUTICAL DEVELOPMENT* AGREEMENT
Pharmaceutical Development Agreement • May 23rd, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

PHARMACEUTICAL DEVELOPMENT AGREEMENT TO DEVELOP A MULTIDOSE INJECTION FOR BIM 44058*
Pharmaceutical Development Agreement • March 10th, 2015 • Radius Health, Inc. • Pharmaceutical preparations • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation with its principal office at Beaufour Ipsen Industrie S.A.S, rue d’Ethe Virton, 28100, France (“Ipsen”).

Pharmaceutical Development Agreement for Medivation Dimebon Pharmaceutical Development
Pharmaceutical Development Agreement • March 11th, 2005 • Orion Acquisition Corp Ii • Blank checks

To verify and/or modify and qualify analytical methods for active pharmaceutical ingredient (API) and drug product, develop a 10 mg immediate release tablet that matches the current Russian tablet in dose, weight and size (Product), manufacture clinical trial material (CTM) of Product and matching Placebo, and conduct stability testing on CTM for Medivation Inc. (Client).

AMENDMENT N°2 TO PHARMACEUTICAL DEVELOPMENT* AGREEMENT
Pharmaceutical Development Agreement • May 23rd, 2011 • Radius Health, Inc. • Blank checks • New York

BEAUFOUR IPSEN INDUSTRIE S.A.S., a French corporation incorporated under the laws of France, located at rue d’Ethe Virton, 28100, France, duly represented by Jean-Pierre Dubuc, President,

Zyber – Macoven Pharmaceuticals Agreement
Pharmaceutical Development Agreement • March 15th, 2010 • Pernix Therapeutics Holdings, Inc. • Real estate investment trusts • Louisiana

An agreement (“AGREEMENT”) is made this 27th day of July, 2009 by and between Zyber Pharmaceuticals, Inc. (“Zyber”), a Louisiana Corporation having an office at 208 East Bank Drive, Gonzales, Louisiana 70737 and Macoven Pharmaceuticals, LLC. (“Macoven Pharmaceuticals”), a Louisiana Limited Liability Company. Zyber and Macoven Pharmaceuticals may be collectively referred to as the “Parties.”

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