Pharmaceutical Manufacturing and Supply Agreement Sample Contracts

Third Amendment to Pharmaceutical Manufacturing and Supply Agreement
Pharmaceutical Manufacturing and Supply Agreement • March 16th, 2017 • Omeros Corp • Pharmaceutical preparations

This is an Amendment (this “Amendment”) to the Pharmaceutical Manufacturing and Supply Agreement dated March 5, 2014, as previously amended July 7, 2015 and August 24, 2016 between DSM Pharmaceuticals, Inc. (“DSM”) and Omeros Corporation (“Omeros”) (the “Master Agreement”), and is entered into as of December 05, 2016 (the “Amendment Effective Date”). All initially capitalized terms in this Amendment shall have the same meaning as set forth in the Master Agreement unless otherwise defined herein.

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AMENDMENT NO. 2 TO PHARMACEUTICAL MANUFACTURING AND SUPPLY AGREEMENT
Pharmaceutical Manufacturing and Supply Agreement • November 6th, 2015 • Amag Pharmaceuticals Inc. • Pharmaceutical preparations

This AMENDMENT NO. 2 (this “Amendment”), dated this 19th day of June, 2015 to the Pharmaceutical Manufacturing and Supply Agreement dated January 8, 2010, as amended (collectively, the “Agreement”), is made by and between AMAG Pharmaceuticals, Inc. (“AMAG”) and Patheon Manufacturing Services LLC (as assignee from DPI Newco LLC as assignee from DSM Pharmaceuticals, Inc.) (hereinafter “PMSLLC”).

AMENDMENT NO. 1 TO PHARMACEUTICAL MANUFACTURING AND SUPPLY AGREEMENT
Pharmaceutical Manufacturing and Supply Agreement • November 7th, 2014 • Amag Pharmaceuticals Inc. • Pharmaceutical preparations

This AMENDMENT NO. 1 (this “Amendment”), dated this 5th day of July, 2014 to the Pharmaceutical Manufacturing and Supply Agreement dated January 8, 2010, is made by and between AMAG Pharmaceuticals, Inc. (“AMAG”) and Patheon Manufacturing Services LLC (as assignee from DSM Pharmaceuticals, Inc.) (“PMSLLC”).

PHARMACEUTICAL MANUFACTURING AND SUPPLY AGREEMENT
Pharmaceutical Manufacturing and Supply Agreement • August 8th, 2013 • Discovery Laboratories Inc /De/ • Biological products, (no disgnostic substances) • New York

THIS PHARMACEUTICAL MANUFACTURING AND SUPPLY AGREEMENT (this “Agreement”) is made effective as of this 7th day of August 2013, by and between DSM Pharmaceuticals, Inc., a Delaware corporation with principal place of business at 5900 Martin Luther King Hwy., Greenville, North Carolina 27834 (“DSM”) and Discovery Laboratories, Inc., a Delaware corporation with principal place of business at 2600 Kelly Road, Suite 100, Warrington, PA 18976-3622 (“Discovery Labs”); (each individually a “Party” and collectively the “Parties”).

SUPPLY AGREEMENT
Pharmaceutical Manufacturing and Supply Agreement • May 12th, 2014 • Omeros Corp • Pharmaceutical preparations • New York

† DESIGNATES PORTIONS OF THIS DOCUMENT THAT HAVE BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT FILED SEPARATELY WITH THE COMMISSION

First Amendment to Pharmaceutical Manufacturing and Supply Agreement
Pharmaceutical Manufacturing and Supply Agreement • November 9th, 2015 • Omeros Corp • Pharmaceutical preparations

This is an Amendment (this “Amendment”) to the Pharmaceutical Manufacturing and Supply Agreement dated March 5, 2014 between DSM Pharmaceuticals, Inc. (“DSM”) and Omeros Corporation (“Omeros”) (the “Master Agreement”), and is entered into as of July 7, 2015 (the “Amendment Effective Date”). All initially capitalized terms in this Amendment shall have the same meaning as set forth in the Master Agreement unless otherwise defined herein.

PHARMACEUTICAL MANUFACTURING AND SUPPLY AGREEMENT Dated: January 8, 2010 By and Between DSM PHARMACEUTICALS, INC. Greenville, NC and AMAG Pharmaceuticals, Inc. Lexington, MA
Pharmaceutical Manufacturing and Supply Agreement • November 7th, 2012 • Amag Pharmaceuticals Inc. • Pharmaceutical preparations

THIS PHARMACEUTICAL MANUFACTURING AND SUPPLY AGREEMENT (this “Agreement”) is made effective as of this 8th day of January 2010 (the “Effective Date”), by and between DSM Pharmaceuticals, Inc., a Delaware corporation with principal place of business at 5900 Martin Luther King Hwy., Greenville, North Carolina 27834 (“DSM”) and AMAG Pharmaceuticals, Inc., a Delaware corporation with principal place of business at 100 Hayden Avenue, Lexington, MA 02421 (“AMAG”); (each individually a “Party” and collectively the “Parties”).

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