Registration Rights Waiver and Amendment Sample Contracts

CADENCE PHARMACEUTICALS, INC. REGISTRATION RIGHTS WAIVER AND AMENDMENT November 29, 2007
Registration Rights Waiver and Amendment • December 3rd, 2007 • Cadence Pharmaceuticals Inc • Pharmaceutical preparations

Reference is made to the Amended and Restated Investor Rights Agreement (the “Investor Rights Agreement”), dated as of February 21, 2006, by and between Cadence Pharmaceuticals, Inc. (the “Company”) and the investor parties thereto (the “Holders”). All capitalized terms used herein and not otherwise defined shall have the meanings assigned to such terms in the Investor Rights Agreement.

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OREXIGEN THERAPEUTICS, INC. REGISTRATION RIGHTS WAIVER AND AMENDMENT January 6, 2008
Registration Rights Waiver and Amendment • January 7th, 2008 • Orexigen Therapeutics, Inc. • Pharmaceutical preparations

Reference is made to the Second Amended and Restated Investors’ Rights Agreement (the “Investors’ Rights Agreement”), dated as of November 20, 2006, by and among Orexigen Therapeutics, Inc. (the “Company”) and the investor parties thereto (the “Holders”). All capitalized terms used herein and not otherwise defined shall have the meanings assigned to such terms in the Investors’ Rights Agreement.

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