Sodium Gamma Hydroxybutyrate Development and Supply Agreement Sample Contracts

Amendment No. 1 to Sodium Gamma Hydroxybutyrate Development and Supply Agreement
Sodium Gamma Hydroxybutyrate Development and Supply Agreement • March 27th, 2007 • Jazz Pharmaceuticals Inc • Pharmaceutical preparations

Amendment No. 1, dated February 7, 2005 (this “Amendment”), between Orphan Medical, Inc., a Delaware corporation (“Orphan”), and Lonza, Inc., a New York corporation (“Supplier”).

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Amendment No. 1 to Sodium Gamma Hydroxybutyrate Development and Supply Agreement
Sodium Gamma Hydroxybutyrate Development and Supply Agreement • May 24th, 2007 • Jazz Pharmaceuticals Inc • Pharmaceutical preparations

Amendment No. 1, dated February 7, 2005 (this “Amendment”), between Orphan Medical, Inc., a Delaware corporation (“Orphan”), and Lonza, Inc., a New York corporation (“Supplier”).

Amendment No.2 to Sodium Gamma Hydroxybutyrate Development and Supply Agreement
Sodium Gamma Hydroxybutyrate Development and Supply Agreement • May 24th, 2007 • Jazz Pharmaceuticals Inc • Pharmaceutical preparations • New York

This Amendment No.2 (the “Amendment”) to the Sodium Gamma Hydroxybutyrate Development and Supply Agreement dated November 6, 1996, as amended, is entered into as of March 30, 2007 (the “Execution Date”) between Jazz Pharmaceuticals, Inc., a Delaware corporation (“Jazz Pharmaceuticals”) and Lonza, Inc., a New York corporation (“Supplier”).

Amendment No. 2 to Sodium Gamma Hydroxybutyrate Development and Supply Agreement
Sodium Gamma Hydroxybutyrate Development and Supply Agreement • April 20th, 2007 • Jazz Pharmaceuticals Inc • Pharmaceutical preparations • New York

This Amendment No. 2 (the “Amendment”) to the Sodium Gamma Hydroxybutyrate Development and Supply Agreement dated November 6, 1996, as amended, is entered into as of March 30, 2007 (the “Execution Date”) between Jazz Pharmaceuticals, Inc., a Delaware corporation (“Jazz Pharmaceuticals”) and Lonza, Inc., a New York corporation (“Supplier”).

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