Active Substructure definition

Active Substructure means the [ * ] structure that is [ * ] of a Compound or Compound Derivative and which has been identified or confirmed against antibacterial or antifungal screens under the Work Plan.
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Active Substructure means the minimum pharmacophore that is responsible for the activity of a Lead Compound or Analog.
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Examples of Active Substructure in a sentence

  • In the event IBP makes a determination to commence human clinical trials of any particular Product or Product(s), the Parties will discuss whether it is practical to assign to IBP any of the patent applications or patents arising from Program Inventions that are specific to the Product in question, or the Compound or Compound Derivative contained therein, or related compounds within the same Active Substructure.

  • Within [ * ] of its selection, the Industry Expert shall confer with the Parties for no longer than [ * ] after he or she receives information from each Party supporting its position on the structure of the Active Substructure or whether the compound should be deemed a “Compound Derivative” and make his or her determination.

  • For purposes of this Section 4.14, a "Derivative" shall mean a compound that has the same, or a substantially similar, Active Substructure as a particular Collaboration Compound, where an "Active Substructure" means those portions of such Collaboration Compound that contribute materially to the activity of such compound against the applicable Mammalian Target.

  • Within [***] of its selection, the Industry Expert shall confer with the Parties for no longer than [***] after he or she receives information from each Party supporting its position on the structure of the Active Substructure or whether the compound should be deemed a "Compound Derivative" and make his or her determination.

Related to Active Substructure

  • Radioactive substance means a substance that emits ionizing

  • Pipelines means those pipelines within the Storage Facility that connect the Tanks to one another and to the receiving and delivery flanges of the Storage Facility.

  • Diameter means the diameter of the stem of a tree measured outside the bark at a specified point of measurement.

  • Underground storage tank or “UST” means any one or combination of tanks (including underground pipes connected thereto) that is used to contain an accumulation of regulated substances, and the volume of which (including the volume of underground pipes connected thereto) is 10 percent or more beneath the surface of the ground. This term does not include any:

  • generation facility means a facility for generating electricity or providing ancillary services, other than ancillary services provided by a transmitter or distributor through the operation of a transmission or distribution system, and includes any structures, equipment or other things used for that purpose;

  • Project Site(s) means the place(s) specified in the SCC for the supply and installation of the System.

  • Cogeneration facility means a power plant in which the heat or steam is also used for industrial or commercial heating or cooling purposes and that meets Federal Energy Regulatory Commission standards for qualifying facilities under the Public Utility Regulatory Policies Act of 1978 (16

  • Material of Environmental Concern means and includes pollutants, contaminants, hazardous wastes, and toxic, radioactive, caustic or otherwise hazardous substances, including petroleum, its derivatives, by-products and other hydrocarbons, or any substance having any constituent elements displaying any of the foregoing characteristics.

  • Project site, where applicable, means the place indicated in bidding documents.

  • Power Plant means a facility for the generation of

  • Transportation Facilities means any physical facility that moves or assist in the movement of people or goods including facilities identified in OAR 660-012-0020 but excluding electricity, sewage, and water systems.

  • Tank means an enclosed space which is formed by the permanent structure of a ship and which is designed for the carriage of liquid in bulk.