Gene Therapy Product definition

Gene Therapy Product means an AAV that delivers one or more therapeutic transgenes to a patient.

Gene Therapy Product means, with respect to a pharmaceutical product, that such pharmaceutical product inserts one or more functional genes into a patient’s cells using an adeno associated virus. For clarity, gene therapy products do not include genome editing, in which genetic engineering is used to insert, delete or replace DNA in the genome of an organism using engineered nucleases.

Gene Therapy Product means any [***] product that delivers [***] for purposes of [***].

Examples of Gene Therapy Product in a sentence

• Orchard will promptly and in any event within [***] days notify UCLB in writing of the First Commercial Sale of each Gene Therapy Product in each country within the Territory.

• Only one Milestone Payment shall be payable per achievement of a Milestone Event for a particular Gene Therapy Product (which in the case of an LCR-EFS Platform Product means one being approved for a different and distinct therapeutic indication, as against all other indications for which an approval is obtained for any other LCR-EFS Platform Product(s)).

• The failure of Introgen to develop successfully any Target Gene Therapy Product will not in and of itself constitute a breach by Introgen of any representation, warranty, covenant or other obligation under this Agreement, the Delivery Technology License Agreement or the Target Gene License Agreement.

• If a Gene Therapy Product containing transduced cells also meets the definition of an MSC Product, it shall be considered as an MSC Product for the purpose of determining milestone payments under this Agreement, and only the milestone payments appropriate for the Bone Therapy Area or the Cartilage Therapy Area, as the case may be, shall be payable by Novartis.

• No Royalty shall be payable on supplies between Orchard, its Affiliates or its Sub-licensees (or any combination of them) unless there is no subsequent sale to a Third Party in an arm’s length transaction for a cash or non-cash consideration within [***] months of that first sale, in which case the Royalty will be calculated on the basis of the open market price for the Gene Therapy Product so supplied.

More Definitions of Gene Therapy Product

Gene Therapy Product means any product containing a virus-based vector that delivers one or more transgenes to a human or animal subject.

Gene Therapy Product means a pharmaceutical product (or proposed or prospective pharmaceutical product) that inserts one or more functional genes or proteins into a patient’s CNS or PNS cells using a parvovirus vector, including but not limited to an AAV. For clarity, Gene Therapy Products [*]. For clarity, [*].

Gene Therapy Product means any nucleic acid molecule, other than an Antisense Inhibitor or Oligonucleotide, that is introduced into human cells for the treatment or prevention of any disease, condition or risk based on modifying the expression of the target gene or modifying the genetic code of the target gene.

Gene Therapy Product means a Virus Vector, including without limitation AAV, that delivers a polynucleotide to certain cells of a patient for a purpose in the Field. Gene Therapy Products include, but are not limited to, Development Candidates, other Collaboration Candidates and Collaboration Products.

Gene Therapy Product means a pharmaceutical product which has the following characteristics:

Gene Therapy Product means a pharmaceutical product (or proposed or prospective pharmaceutical product) that inserts one or more functional genes into a patient’s CNS or PNS cells using a parvovirus vector, including but not limited to an AAV. For clarity, Gene Therapy Products may include [*], but do not include [*]. For clarity, this provision shall not be construed to affect [*].”

Gene Therapy Product means a product based on the transfer or use of DNA, RNA, or hybrids thereof to treat or prevent disease by means of ex vivo or in vivo gene delivery, including without limitation the use of both viral and non-viral gene transfer systems.