Examples of ISIS 14803 in a sentence
The ability of ISIS 14803 to inhibit HCV gene expression in cell culture and in a novel in vivo mouse model of HCV gene expression demonstrates the potential of this compound as a drug development candidate.
Preclinical toxicology and pharmacokinetics studies of ISIS 14803 will begin in early 1999.
Upon binding to the complementary target sequence, ISIS 14803 inhibits expression of HCV proteins required for viral replication.
ISIS 14803 our antisense inhibitor of HCV, ISIS 14803, may represent a significant therapeutic advance in treating this serious viral epidemic.
In conjunction with its continuing restructuring efforts, Elan concluded its participation in the HepaSense collaboration in 2002 and the Company reacquired all rights to ISIS 14803, the compound that the collaboration had been developing.
Through this agreement, Isis eliminated all future royalties to Elan related to the oral delivery platform developed within the Orasense collaboration and to ISIS 14803, Isis’ antisense drug for the treatment of the hepatitis C virus, which is currently in Phase 2 clinical trials for the treatment of hepatitis C and was the focus of the HepaSense collaboration.
In conjunction with its continuing restructuring efforts, Elan concluded its participation in the HepaSensecollaboration in 2002 and the Company reacquired all rights to ISIS 14803, the compound that the collaboration had been developing.