Large Molecule definition

Large Molecule means a molecule that is not a Polypeptide or a Small Molecule.
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Large Molecule means a polypeptide, protein, antibody (or any similar molecule which is produced by introduction of recombinant DNA into appropriate hosts) and nucleic acid molecules (e.g., DNA encoding such molecules, antisense oligonucleotides).
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Large Molecule means a *****.
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Examples of Large Molecule in a sentence

  • For example, if the Licensee develops a particular Licensed Product to a Target, which Licensed Product incorporates a Large Molecule, and pays development milestones [***], no payment shall be due under such development milestones on the Licensee’s development of another Licensed Product to the same Target, which Licensed Product incorporates a Large Molecule, including the same or different Large Molecule.

  • Likewise, if the Licensee develops a particular Licensed Product to a Target, which Licensed Product incorporates a Large Molecule, and pays development milestones [***], payment shall be due under such development milestones on the Licensee’s development of another Licensed Product to the same Target, which Licensed Product incorporates a Small Molecule or a Polypeptide.

  • Payment of ***** Dollars (US $*****) upon either (a) Proof of Principle (as defined below) in the Research Field with a Small Molecule or Large Molecule in an appropriate animal model (to be determined by the JRC) or (b) initiation of pre-clinical toxicology on a clinical candidate.

  • Payment of ***** Dollars (US $*****) upon either (a) the establishment, using appropriate in vivo studies (to be determined by the JRC), that the ***** and/or ***** has an effect ***** predicted by the *****, or (b) the initiation of high-throughput chemistry screening in the case of a Small Molecule or synthesis of a therapeutic antibody or protein suitable for in vitro or in vivo screening in the case of a Large Molecule.

  • The Parties hereby agree that, for each indication of a Product, GENE's Early Contribution Level or Late Contribution Level, as the case may be, shall remain the same for any presentation or formulation of a Product containing the same Small Molecule or Large Molecule.

  • Sciences will collaborate on offering three (3) On Demand training courses: Biopharmaceutical: Introduction to Large Molecule Therapeutics, Biopharmaceutical: CMC Aspects and Biopharmaceutical: C&GT and ATMP in Portuguese.

  • The Parties hereby agree that, for each indication of a Product, GENE’s Early Contribution Level or Late Contribution Level, as the case may be, shall remain the same for any presentation or formulation of a Product containing the same Small Molecule or Large Molecule.


More Definitions of Large Molecule

Large Molecule means [**].
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Related to Large Molecule

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.

  • Collaboration Compound means any of the following: (a) FG-4592, (b) any HIF Compound (other than FG-4592) that is added to this Agreement pursuant to Section 3.6, and (c) any salts, esters, complexes, chelates, crystalline and amorphous morphic forms, pegylated forms, enantiomers (excluding regioisomers), prodrugs, solvates, metabolites and catabolites of any of the foregoing ((a) or (b)).

  • Licensed Compound means [***].

  • Licensed Antibody means (a) any Licensed Program Antibody and (b) any other Antibody that is a variant, fragment, derivative or other modification of a Licensed Program Antibody, that (i) Targets the Licensed Target, (ii) is made by or on behalf of Celgene or its Affiliates or Sublicensees during the Term in the course of its activities performed under this Agreement (or during the term of the Licensed Program U.S. License Agreement in the course of its activities performed thereunder) and (iii) is claimed (or was claimed in an issued Patent that has subsequently expired) as a composition of matter in a Licensed Program Patent set forth on Schedule 1.46(b), a Prothena Licensed Collaboration Patent set forth on Schedule 1.63, or Joint Program Patent (as defined in the Master Collaboration Agreement) as applicable, or any substitutions, divisionals, continuations, continuations-in-part, reissues, renewals, registrations, confirmations, re-examinations, extensions, supplementary protection certificates and the like of any such Licensed Program Patents, Prothena Licensed Collaboration Patents or Joint Program Patents (as defined in the Master Collaboration Agreement).

  • Opioid antagonist means a drug that binds to opioid