Limit of Detection definition

Limit of Detection or “LOD” means the minimum concentration of a substance that can be measured and reported with ninety-nine percent (99%) confidence that the analyte concentration is greater than zero (0) for a particular analytical method and sample matrix.
Limit of Detection or “LOD” means the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) within a stated confidence limit (generally 1%).
Limit of Detection means the lowest concentration level that can be determined to be statistically different from a blank.

Examples of Limit of Detection in a sentence

  • Concentrations less than the Limit of Quantitation (LOQ) and greater than or equal to the Limit of Detection (LOD) shall be reported by the permittee on the discharge monitoring report forms as the actual measured value.

  • Limit of Detection (LOD): The lowest concentration at which a measurand can be identified, but (for quantitative assays) the concentration cannot be accurately calculated.

  • The Limit of Detection (LoD) of the Sofia SARS Antigen FIA was determined using limiting dilutions of heat-inactivated SARS-CoV-2 (bei Resources NR-52286).

  • The LOD95 (Limit of Detection) defines the number of target sequences (copy number) that can be detected in ≥ 95% of reactions.

  • Limit of Detection (LoD) is the lowest concentration of analyte that is detected at a rate of no less than 95%.


More Definitions of Limit of Detection

Limit of Detection or "LOD" means an estimate of the minimum amount of a substance that an analytical process can reliably detect. An LOD is analyte and matrix specific and may be laboratory dependent.
Limit of Detection or “LOD” means a measurement of the concentration of a substance that can be measured and reported with ninety-nine percent (99%) confidence that the analyte concentration is greater than zero (0) for a particular analytical method and sample matrix. The LOD is equivalent to the method detection level or MDL.
Limit of Detection or “LOD” means the lowest con- centration or amount of analyte that can be identified, measured, and reported with confidence that the concentration is not a false positive value. For department purposes, the LOD approximates the MDL and is determined per the method cited in sub. (46).
Limit of Detection or “LOD” means the lowest con- centration level that can be determined to be significantly differ- ent from a blank for that analytical test method and sample matrix.
Limit of Detection means the output signal or concentration value above which it can be affirmed, with a stated level of confidence that a sample is different from a blank sample containing no determinand of interest;
Limit of Detection or “LOD” means the lowest concentration or amount of analyte that can be identified, measured, and reported with confidence that the concentration is not a false positive value. The department considers the LOD to be equivalent to the method detection limit and is determined under the method cited in sub. (46).
Limit of Detection means the lowest concentration level that can be determined to be statistically different from a blank sample for that analytical test method and sample matrix.